CNTN6 Antibody

中文名稱：

CNTN6兔多克隆抗體
貨號：

CSB-PA973774
規(guī)格：

￥2024
圖片：
Western blot analysis of extracts from Jurkat cells and A549 cells, using CNTN6 antibody.
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) CNTN6 Polyclonal antibody
Uniprot No.：

Q9UQ52
基因名：

CNTN6
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Synthesized peptide derived from internal of Human CNTN6.
免疫原種屬：

Homo sapiens (Human)
克隆類型：

Polyclonal
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:3000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination.
基因功能參考文獻：
1. Clinical investigations of the patients carrying CNTN5 or CNTN6 variants showed that they were hypersensitive to sounds (a condition called hyperacusis) and displayed changes in wave latency within the auditory pathway. PMID: 27166760
2. CNTN6 copy number variants (duplications) were associated with increased risk of Tourette syndrome. PMID: 28641109
亞細(xì)胞定位：

Cell membrane; Lipid-anchor, GPI-anchor.
蛋白家族：

Immunoglobulin superfamily, Contactin family
組織特異性：

Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord.
數(shù)據(jù)庫鏈接：

HGNC: 2176

OMIM: 607220

KEGG: hsa:27255

STRING: 9606.ENSP00000341882

UniGene: Hs.387300