pfo
Perfringolysin O (PFO)是由肉毒梭菌（Clostridium perfringens）產(chǎn)生的毒素。其結(jié)構(gòu)是一個大的單亞單位蛋白，具有約497個氨基酸，含有多個β-折疊和α螺旋結(jié)構(gòu)。PFO主要通過與細胞膜中的膽固醇結(jié)合，形成聚合物，并形成可通透的孔道，導(dǎo)致細胞膜的破壞和溶解。這種溶孔作用會破壞細胞的完整性，導(dǎo)致溶解和細胞死亡。PFO主要通過膽固醇結(jié)合并引發(fā)細胞膜的溶解，導(dǎo)致細胞內(nèi)外離子平衡失調(diào)，從而影響細胞的生存和功能。PFO和其變體可以用作生物學(xué)研究中的細胞膜溶解工具，用于探究細胞膜通透性和細胞膜受損的影響。在肉毒梭菌感染的情況下，PFO被認為是該菌致病性的重要因素之一，它參與了細胞的溶解和組織損傷，因此在了解和研究感染機制、藥物開發(fā)等方面有一定的應(yīng)用價值。
熱銷產(chǎn)品
Recombinant Clostridium perfringens Perfringolysin O (pfo)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS Analysis result of CSB-EP314820CMB could indicate that this peptide derived from E.coli-expressed Clostridium perfringens (strain 13 / Type A) pfo.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS Analysis result of CSB-EP314820CMB could indicate that this peptide derived from E.coli-expressed Clostridium perfringens (strain 13 / Type A) pfo.
pfo Antibodies
pfo for Clostridium perfringens
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA314820HA01CMB | pfo Antibody | Clostridium perfringens | ELISA, WB |
| CSB-PA314820HB01CMB | pfo Antibody, HRP conjugated | Clostridium perfringens | ELISA |
| CSB-PA314820HC01CMB | pfo Antibody, FITC conjugated | Clostridium perfringens | |
| CSB-PA314820HD01CMB | pfo Antibody, Biotin conjugated | Clostridium perfringens | ELISA |
pfo Proteins
pfo Proteins for Clostridium perfringens
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP314820CMB CSB-BP314820CMB CSB-MP314820CMB CSB-EP314820CMB-B |
Recombinant Clostridium perfringens Perfringolysin O (pfo) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
pfo Proteins for Clostridium perfringens (strain 13 / Type A)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-EP314820CMB | Recombinant Clostridium perfringens Perfringolysin O (pfo) | E.coli |
