YTHDF1
YTHDF1，即YTH結(jié)構(gòu)域家族蛋白1，別名YTHDF。YTHDF1是一種RNA結(jié)合蛋白，屬于m6A（N6-甲基腺苷）修飾的“閱讀器”，在mRNA的代謝過程中發(fā)揮著重要作用。YTHDF1的作用機(jī)制涉及其YTH結(jié)構(gòu)域與m6A修飾的RNA的結(jié)合，這一過程可能影響mRNA的穩(wěn)定性、翻譯效率和亞細(xì)胞定位。此外，YTHDF1還參與了多種信號(hào)通路，對(duì)腫瘤細(xì)胞的增殖、代謝重編程和免疫逃逸等方面發(fā)揮著重要作用。YTHDF1的異常表達(dá)與多種疾病的發(fā)生發(fā)展有關(guān)，尤其是在癌癥中，YTHDF1的過表達(dá)與腫瘤的不良預(yù)后和對(duì)化療及免疫療法的耐藥性相關(guān)。YTHDF1被認(rèn)為是未來癌癥治療的一個(gè)有前途的靶標(biāo)和新型腫瘤生物標(biāo)志物。
熱銷產(chǎn)品
Recombinant Human YTH domain-containing family protein 1 (YTHDF1), partial (CSB-EP874843HU1a0)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
YTHDF1 Antibody (CSB-PA132305)
驗(yàn)證數(shù)據(jù)
Western blot analysis of extracts from 293 cells, using YTHDF1 antibody.
YTHDF1 Antibodies
YTHDF1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA026279GA01HU | YTHDF1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA132305 | YTHDF1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA002062 | YTHDF1 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
YTHDF1 Proteins
YTHDF1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP874843HU | Recombinant Human YTH domain-containing family protein 1 (YTHDF1) | Yeast |
| CSB-EP874843HU | Recombinant Human YTH domain-containing family protein 1 (YTHDF1) | E.coli |
| CSB-BP874843HU CSB-MP874843HU CSB-EP874843HU-B |
Recombinant Human YTH domain-containing family protein 1 (YTHDF1) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP874843HU1a0 | Recombinant Human YTH domain-containing family protein 1 (YTHDF1), partial | E.coli |
| CSB-MP874843HU1 | Recombinant Human YTH domain-containing family protein 1 (YTHDF1), partial | Mammalian cell |
