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WARS1

WARS1,全稱為色氨酰tRNA合成酶1,是一種參與蛋白質(zhì)合成的重要酶類。該蛋白在細(xì)胞內(nèi)負(fù)責(zé)將色氨酸氨?;鶊F(tuán)連接到對(duì)應(yīng)的tRNA分子上,確保色氨酸在蛋白質(zhì)合成過(guò)程中的正確添加。WARS1蛋白常見(jiàn)別名包括TRY1和TARS1,其結(jié)構(gòu)特征使其能夠高效催化氨酰化反應(yīng),對(duì)維持蛋白質(zhì)合成的準(zhǔn)確性和效率至關(guān)重要。此外,WARS1蛋白還與某些疾病的發(fā)生發(fā)展密切相關(guān),如神經(jīng)發(fā)育障礙伴小頭畸形等。在藥物研發(fā)領(lǐng)域,針對(duì)WARS1蛋白的抑制劑已被研究用于治療癌癥和自身免疫性疾病,部分藥物已進(jìn)入臨床試驗(yàn)階段,顯示出良好的應(yīng)用前景。

熱銷產(chǎn)品

Recombinant Human Tryptophan--tRNA ligase, cytoplasmic (WARS1) (CSB-MP025965HU)

驗(yàn)證數(shù)據(jù)

CSB-MP025965HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

WARS1 Recombinant Monoclonal Antibody (CSB-RA293319A0HU)

驗(yàn)證數(shù)據(jù)

CSB-RA293319A0HU

Western Blot
Positive WB detected in: A-431 whole cell lysate(30μg), HeLa whole cell lysate, HL-60 whole cell lysate(30μg)
All lanes: WARS1 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 53 kDa
Observed band size: 53 kDa
Exposure time: 3min

CSB-RA293319A0HU

Overlay Peak curve showing HepG2 cells stained with CSB-RA293319A0HU (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100 for 10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 35min at 4℃.Control antibody (green line) was Rabbit IgG (1ug/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.

Human tryptophanyl-tRNA synthetase,WARS ELISA Kit (CSB-E11789h)

驗(yàn)證數(shù)據(jù)

CSB-E11789h 標(biāo)準(zhǔn)曲線

貨號(hào):CSB-E11789h

規(guī)格:96T/48T

靈敏度:0.078 ng/mL

檢測(cè)范圍:0.312 ng/mL-20 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

WARS1 Antibodies

WARS1 for Homo sapiens (Human)

WARS1 Proteins

WARS1 Proteins for Homo sapiens (Human)

WARS1 ELISA Kit

WARS1 ELISA Kit for Homo sapiens (Human)



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