TREM1

TREM1，即髓樣細(xì)胞觸發(fā)受體1，別名CD354、TREM-1。TREM1是一種在中性粒細(xì)胞、單核細(xì)胞和巨噬細(xì)胞表面表達(dá)的髓系細(xì)胞觸發(fā)受體，屬于免疫球蛋白超家族成員。TREM1與DAP12結(jié)合，通過DAP12中的ITAMs（免疫受體酪氨酸激活基序）在酪氨酸殘基上磷酸化，激活下游的ZAP70和SYK蛋白酪氨酸激酶，進(jìn)而通過PI3K、PLC-Gamma和ERK等途徑導(dǎo)致下游信號轉(zhuǎn)導(dǎo)，誘導(dǎo)促炎癥細(xì)胞因子、趨化因子和細(xì)胞表面分子的表達(dá)。TREM1通過進(jìn)一步增加促炎癥細(xì)胞因子的產(chǎn)生來擴(kuò)大Toll樣受體誘導(dǎo)的炎癥，參與調(diào)節(jié)急性和慢性炎癥反應(yīng)，在多種感染性疾病、自身免疫性疾病和腫瘤免疫中發(fā)揮重要作用。

熱銷產(chǎn)品

TREM1 Antibody (CSB-PA004863)

驗證數(shù)據(jù)

Western Blot analysis of THP-1 mouse heart cells using TREM-1 Polyclonal Antibody

Human Triggering Receptor Expresses on Myeloid Cells-1,TREM-1 ELISA Kit (CSB-E04836h)

驗證數(shù)據(jù)

貨號：CSB-E04836h

規(guī)格：96T/48T

靈敏度：7.81 pg/mL

檢測范圍：31.25 pg/mL-2000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

TREM1 Antibody

TREM1 Protein

TREM1 ELISA Kit

TREM1 Antibodies

TREM1 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA024404GA01HU	TREM1 Antibody	Human	ELISA,WB
CSB-PA004863	TREM1 Antibody	Human	WB, ELISA
CSB-PA024404ESR2HU	TREM1 Antibody	Human	ELISA, WB

TREM1 Proteins

TREM1 Proteins for Pongo abelii (Sumatran orangutan)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP024404PYX CSB-EP024404PYX CSB-BP024404PYX CSB-MP024404PYX CSB-EP024404PYX-B	Recombinant Pongo abelii Triggering receptor expressed on myeloid cells 1 (TREM1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TREM1 Proteins for Bos taurus (Bovine)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP024404BO CSB-EP024404BO CSB-BP024404BO CSB-MP024404BO CSB-EP024404BO-B	Recombinant Bovine Triggering receptor expressed on myeloid cells 1 (TREM1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TREM1 Proteins for Sus scrofa (Pig)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP024404PI CSB-EP024404PI CSB-BP024404PI CSB-MP024404PI CSB-EP024404PI-B	Recombinant Pig Triggering receptor expressed on myeloid cells 1 (TREM1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TREM1 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP024404MO CSB-EP024404MO CSB-BP024404MO CSB-MP024404MO CSB-EP024404MO-B	Recombinant Mouse Triggering receptor expressed on myeloid cells 1 (Trem1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TREM1 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP024404HU CSB-EP024404HU CSB-BP024404HU CSB-EP024404HU-B	Recombinant Human Triggering receptor expressed on myeloid cells 1 (TREM1), partial	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli