TRAM1
TRAM1，即易位相關(guān)膜蛋白1，別名TRAM、PNAS8、TRAMP。這是一種在人類細(xì)胞內(nèi)質(zhì)網(wǎng)中表達(dá)的多通道膜蛋白。TRAM1的作用機(jī)制涉及影響糖基化，并在新生多肽鏈的易位暫停期間，通過(guò)調(diào)節(jié)哪些結(jié)構(gòu)域?qū)Π|(zhì)溶膠可見(jiàn)，來(lái)促進(jìn)分泌蛋白跨內(nèi)質(zhì)網(wǎng)膜的易位。它還可能影響SEC61通道附近的磷脂雙層，從而促進(jìn)蛋白質(zhì)的內(nèi)質(zhì)網(wǎng)運(yùn)輸，并在內(nèi)質(zhì)網(wǎng)應(yīng)激條件下，參與未折疊蛋白反應(yīng)（UPR）中的蛋白質(zhì)降解過(guò)程。TRAM1在多種生物學(xué)過(guò)程中發(fā)揮作用，包括宿主-病毒相互作用、蛋白質(zhì)運(yùn)輸、易位和未折疊蛋白反應(yīng)。異常的TRAM1表達(dá)與多種疾病相關(guān)，如Meckel綜合征2型、Oropouche熱、神經(jīng)細(xì)胞脂褐質(zhì)沉積癥8型Northern癲癇變體、Varadi-Papp綜合征等。
熱銷產(chǎn)品
Recombinant Human Translocating chain-associated membrane protein 1 (TRAM1), partial
來(lái)源：Yeast
來(lái)源：E.coli
來(lái)源：Baculovirus
來(lái)源：Mammalian cell
來(lái)源：In Vivo Biotinylation in E.coli
TRAM1 Antibodies
TRAM1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA024221GA01HU | TRAM1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
TRAM1 Proteins
TRAM1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP618990HU CSB-EP618990HU CSB-BP618990HU CSB-MP618990HU CSB-EP618990HU-B |
Recombinant Human Translocating chain-associated membrane protein 1 (TRAM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TRAM1 Proteins for Pongo abelii (Sumatran orangutan)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP719168PYX CSB-EP719168PYX CSB-BP719168PYX CSB-MP719168PYX CSB-EP719168PYX-B |
Recombinant Pongo abelii Translocating chain-associated membrane protein 1 (TRAM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TRAM1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP723043RA CSB-EP723043RA CSB-BP723043RA CSB-MP723043RA CSB-EP723043RA-B |
Recombinant Rat Translocating chain-associated membrane protein 1 (Tram1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TRAM1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP852767MO CSB-EP852767MO CSB-BP852767MO CSB-MP852767MO CSB-EP852767MO-B |
Recombinant Mouse Translocating chain-associated membrane protein 1 (Tram1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TRAM1 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP875599BO CSB-EP875599BO CSB-BP875599BO CSB-MP875599BO CSB-EP875599BO-B |
Recombinant Bovine Translocating chain-associated membrane protein 1 (TRAM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
