TPM3
TPM3，全稱為tropomyosin 3，是一種與肌肉細(xì)胞收縮相關(guān)的蛋白。它屬于原肌球蛋白家族，該家族的蛋白能夠結(jié)合在肌動(dòng)蛋白絲上，維持肌動(dòng)蛋白絲的穩(wěn)定性，并調(diào)節(jié)其他肌動(dòng)蛋白結(jié)合蛋白的訪問(wèn)。TPM3蛋白的常見別名包括alpha tropomyosin 3、TPM3_HUMAN、Tpm5、TPMsk3、TRK、TRK ONCOGENE, INCLUDED、Trop 5、Tropomyosin 3、Tropomyosin 3 gamma、Tropomyosin-3、Tropomyosin-5。TPM3蛋白在多種組織中都有表達(dá)，包括骨髓、盲腸和25種其他組織。TPM3蛋白與多種疾病相關(guān)，包括肌肉萎縮癥、肌營(yíng)養(yǎng)不良和癌癥。在癌癥中，TPM3基因突變會(huì)導(dǎo)致融合蛋白的形成，這些融合蛋白可以作為致癌基因。針對(duì)TPM3蛋白的藥物研發(fā)正在積極進(jìn)行中，例如TRK抑制劑，這些藥物有望為癌癥患者提供新的治療選擇。
熱銷產(chǎn)品
Recombinant Human Tropomyosin alpha-3 chain (TPM3) (CSB-EP024106HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TPM3 Antibody (CSB-PA024106LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA024106LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA024106LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA024106LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
TPM3 Antibodies
TPM3 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA024106GA01HU | TPM3 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA024106LA01HU | TPM3 Antibody | Human | ELISA, IHC, IF |
| CSB-PA024106LB01HU | TPM3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA024106LC01HU | TPM3 Antibody, FITC conjugated | Human | |
| CSB-PA024106LD01HU | TPM3 Antibody, Biotin conjugated | Human | ELISA |
TPM3 Proteins
TPM3 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP024106MO CSB-EP024106MO CSB-BP024106MO CSB-MP024106MO CSB-EP024106MO-B |
Recombinant Mouse Tropomyosin alpha-3 chain (Tpm3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TPM3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP024106HU CSB-BP024106HU CSB-MP024106HU CSB-EP024106HU-B |
Recombinant Human Tropomyosin alpha-3 chain (TPM3) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP024106HU | Recombinant Human Tropomyosin alpha-3 chain (TPM3) | E.coli |
TPM3 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP024106PI CSB-EP024106PI CSB-BP024106PI CSB-MP024106PI CSB-EP024106PI-B |
Recombinant Pig Tropomyosin alpha-3 chain (TPM3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TPM3 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP705528BO CSB-EP705528BO CSB-BP705528BO CSB-MP705528BO CSB-EP705528BO-B |
Recombinant Bovine Tropomyosin alpha-3 chain (TPM3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TPM3 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP737211RA CSB-EP737211RA CSB-BP737211RA CSB-MP737211RA CSB-EP737211RA-B |
Recombinant Rat Tropomyosin alpha-3 chain (Tpm3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
