TGFBR1
TGFBR1，即轉(zhuǎn)化生長因子β受體1，別名TGFβR1、ALK5。它是一種絲氨酸/蘇氨酸激酶型受體，由人體細(xì)胞自身的基因編碼。TGFBR1作為TGF-β信號通路的關(guān)鍵組成部分，與TGF-β配體結(jié)合后，激活包括Smad在內(nèi)的多種信號轉(zhuǎn)導(dǎo)通路，從而調(diào)控細(xì)胞的增殖、分化、遷移和凋亡等生物學(xué)過程。TGFBR1在胚胎發(fā)育、組織修復(fù)、免疫調(diào)節(jié)以及腫瘤發(fā)生發(fā)展中發(fā)揮著重要作用，其功能異常與多種疾病相關(guān)，包括纖維化疾病、某些類型的癌癥等，是藥物開發(fā)和疾病治療中的潛在靶點(diǎn)。
熱銷產(chǎn)品
Recombinant Human TGF-beta receptor type-1 (TGFBR1), partial (CSB-EP023451HU1)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TGFBR1 Antibody (CSB-PA004276)
驗證數(shù)據(jù)
Western Blot analysis of HepG2 cells using TGFβ RI Polyclonal Antibody
Western Blot analysis of NIH-3T3 cells using TGFβ RI Polyclonal Antibody
TGFBR1 Antibodies
TGFBR1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA061850 | TGFBR1 (Ab-165) Antibody | Human,Mouse | ELISA,WB,IF |
| CSB-PA004276 | TGFBR1 Antibody | Human,Mouse,Rat | WB, IF, ELISA |
| CSB-PA050248 | Phospho-TGFBR1 (S165) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA699479 | TGFBR1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA206147 | TGFBR1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA023451LA01HU | TGFBR1 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA023451LB01HU | TGFBR1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA023451LC01HU | TGFBR1 Antibody, FITC conjugated | Human | |
| CSB-PA023451LD01HU | TGFBR1 Antibody, Biotin conjugated | Human | ELISA |
TGFBR1 Proteins
TGFBR1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP023451RA CSB-EP023451RA CSB-BP023451RA CSB-MP023451RA CSB-EP023451RA-B |
Recombinant Rat TGF-beta receptor type-1 (Tgfbr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TGFBR1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP023451HU1 CSB-BP023451HU1 CSB-MP023451HU1 CSB-EP023451HU1-B |
Recombinant Human TGF-beta receptor type-1 (TGFBR1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF023451HU | Recombinant Human TGF-beta receptor type-1 (TGFBR1) | in vitro E.coli expression system |
| CSB-EP023451HU1 | Recombinant Human TGF-beta receptor type-1 (TGFBR1), partial | E.coli |
| CSB-MP023451HU2 | Recombinant Human TGF-beta receptor type-1 (TGFBR1), partial | Mammalian cell |
TGFBR1 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP023451BO1 CSB-EP023451BO1 CSB-BP023451BO1 CSB-MP023451BO1 CSB-EP023451BO1-B |
Recombinant Bovine TGF-beta receptor type-1 (TGFBR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF023451BO | Recombinant Bovine TGF-beta receptor type-1 (TGFBR1) | in vitro E.coli expression system |
TGFBR1 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP685610PI CSB-EP685610PI CSB-BP685610PI CSB-MP685610PI CSB-EP685610PI-B |
Recombinant Pig TGF-beta receptor type-1 (TGFBR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TGFBR1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP734134MO CSB-EP734134MO CSB-BP734134MO CSB-MP734134MO CSB-EP734134MO-B |
Recombinant Mouse TGF-beta receptor type-1 (Tgfbr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
