TGFB3

轉(zhuǎn)化生長因子-β3（TGF-β3）是調(diào)控胚胎發(fā)育和組織穩(wěn)態(tài)的重要蛋白，在哺乳動物中也被簡稱為TGFB3。該蛋白屬于轉(zhuǎn)化生長因子超家族成員，與TGF-β1、TGF-β2具有相似結(jié)構(gòu)但獨(dú)特功能，尤其在心臟形態(tài)建成和腭板融合過程中起關(guān)鍵作用。TGFB3通過激活特定胞內(nèi)分子網(wǎng)絡(luò)，影響細(xì)胞增殖、分化及胞外基質(zhì)沉積，異常表達(dá)可能引發(fā)先天性心臟病、腭裂等發(fā)育缺陷，并與肺纖維化、腫瘤轉(zhuǎn)移等病理過程相關(guān)。近年有學(xué)者發(fā)現(xiàn)該蛋白在調(diào)控免疫微環(huán)境和抑制過度瘢痕形成方面具有潛力，相關(guān)抗體藥物如GC1008已進(jìn)入臨床試驗(yàn)，用于特發(fā)性肺纖維化等疾病的干預(yù)。不過由于TGF-β家族成員功能的高度復(fù)雜性，針對TGF-β3的特異性靶向治療仍需突破多重技術(shù)瓶頸。

熱銷產(chǎn)品

Recombinant Human Transforming growth factor beta-3 (TGFB3), partial (CSB-EP023449HU1)

驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TGFB3 Antibody (CSB-PA023449LA01HU)

驗(yàn)證數(shù)據(jù)

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA023449LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA023449LA01HU at dilution of 1:100

Human Transforming Growth factor β3,TGF-β3 ELISA kit (CSB-E13738h)

驗(yàn)證數(shù)據(jù)

貨號：CSB-E13738h

規(guī)格：96T/48T

靈敏度：3.9 pg/mL

檢測范圍：15.6 pg/mL-1000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

TGFB3 Antibody

TGFB3 Protein

TGFB3 ELISA Kit

TGFB3 Antibodies

TGFB3 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA023449GA01HU	TGFB3 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA17749C0Rb	TGFB3 Antibody, FITC conjugated	Human
CSB-PA17749B0Rb	TGFB3 Antibody, HRP conjugated	Human	ELISA
CSB-PA17749D0Rb	TGFB3 Antibody, Biotin conjugated	Human	ELISA
CSB-PA217147	TGFB3 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA004283	TGFB3 Antibody	Human,Mouse,Rat,Monkey	WB, IHC, ELISA
CSB-PA023449LA01HU	TGFB3 Antibody	Human	ELISA, IHC
CSB-PA023449LD01HU	TGFB3 Antibody, Biotin conjugated	Human	ELISA
CSB-PA023449LC01HU	TGFB3 Antibody, FITC conjugated	Human
CSB-PA023449LB01HU	TGFB3 Antibody, HRP conjugated	Human	ELISA
CSB-PA17749A0Rb	TGFB3 Antibody	Human	ELISA, IHC

TGFB3 Proteins

TGFB3 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023449HU CSB-BP023449HU CSB-MP023449HU CSB-EP023449HU-B	Recombinant Human Transforming growth factor beta-3 proprotein (TGFB3), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP023449HU1	Recombinant Human Transforming growth factor beta-3 (TGFB3), partial	E.coli
CSB-EP023449HU	Recombinant Human Transforming growth factor beta-3 proprotein (TGFB3), partial	E.coli
CSB-AP004051HU	Recombinant Human Transforming growth factor beta-3 (TGFB3)(Y340F), partial (Active)	Mammalian cell
CSB-MP023449HU-WD	Recombinant Human Transforming growth factor beta-3 proprotein (TGFB3)，Partial (Active)	Mammalian cell

TGFB3 Proteins for Gallus gallus (Chicken)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023449CH CSB-EP023449CH CSB-BP023449CH CSB-MP023449CH CSB-EP023449CH-B	Recombinant Chicken Transforming growth factor beta-3 (TGFB3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TGFB3 Proteins for Sus scrofa (Pig)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023449PI CSB-EP023449PI CSB-BP023449PI CSB-MP023449PI CSB-EP023449PI-B	Recombinant Pig Transforming growth factor beta-3 (TGFB3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TGFB3 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023449MO CSB-BP023449MO CSB-EP023449MO-B	Recombinant Mouse Transforming growth factor beta-3 (Tgfb3), partial	Yeast Baculovirus In Vivo Biotinylation in E.coli