SSX2
SSX2蛋白，全稱為滑膜肉瘤X斷點(diǎn)蛋白2，也被稱為SSX；HD21；CT5.2；CT5.2A；HOM-MEL-40。該蛋白屬于滑膜肉瘤X (SSX) 斷點(diǎn)蛋白家族，主要作用是作為轉(zhuǎn)錄抑制因子，參與調(diào)節(jié)基因表達(dá)。SSX2蛋白與癌癥的發(fā)生發(fā)展密切相關(guān)，尤其是在滑膜肉瘤中，其基因與染色體18上的滑膜肉瘤易位基因發(fā)生易位，導(dǎo)致基因融合，從而促進(jìn)腫瘤的形成。目前，針對(duì)SSX2蛋白的藥物研發(fā)正在積極推進(jìn)，包括開(kāi)發(fā)針對(duì)SSX2蛋白的TCR-T細(xì)胞療法等，以期提高癌癥治療效果。
熱銷(xiāo)產(chǎn)品
Recombinant Human Protein SSX2 (SSX2) (CSB-EP613674HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
SSX2 Antibody (CSB-PA613674ESR2HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: MDA-MB-231 whole cell lysate(30μg), MCF7 whole cell lysate(30μg), Hela whole cell lysate(30μg), A549 whole cell lysate(30μg), JK whole cell lysate(30μg), 293 whole cell lysate(30μg)
All lanes: SSX2 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/20000 dilution
Predicted band size: 22,26 kDa
Observed band size: 26 kDa
Exposure time: 60s
SSX2 Antibodies
SSX2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA613674ESR2HU | SSX2 Antibody | Human | ELISA, WB |
| CSB-PA613674LA01HU | SSX2 Antibody | Human | ELISA |
| CSB-PA613674LB01HU | SSX2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA778235 | SSX2 Antibody | Human | ELISA,IHC |
SSX2 Proteins
SSX2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP613674HU CSB-BP613674HU CSB-MP613674HU CSB-EP613674HU-B |
Recombinant Human Protein SSX2 (SSX2) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP613674HU | Recombinant Human Protein SSX2 (SSX2) | E.coli |
