SLIT3
SLIT3，全稱為Slit同源物3，是一類分泌到細(xì)胞外的糖蛋白，在人體胚胎發(fā)育和成年組織修復(fù)中都扮演著重要角色。它常被簡(jiǎn)稱為Slit3，部分研究中也會(huì)和血管生長(zhǎng)相關(guān)的分子一同討論。SLIT3能引導(dǎo)細(xì)胞的移動(dòng)方向，比如在胚胎時(shí)期幫助構(gòu)建完整的血管網(wǎng)絡(luò)，讓血管內(nèi)皮細(xì)胞有序排列并形成穩(wěn)定的血管結(jié)構(gòu)；成年后，當(dāng)組織出現(xiàn)缺血或損傷時(shí)，它也能促進(jìn)新血管的生成，幫助恢復(fù)血液供應(yīng)。
要是SLIT3的表達(dá)不對(duì)勁，可能會(huì)和一些健康問題扯上關(guān)系。比如心血管領(lǐng)域，它的水平降低可能導(dǎo)致缺血性疾病的發(fā)生風(fēng)險(xiǎn)上升；有些腫瘤研究也發(fā)現(xiàn)，其表達(dá)變化會(huì)影響腫瘤周圍血管的生長(zhǎng)，進(jìn)而改變腫瘤的發(fā)展進(jìn)程。目前針對(duì)SLIT3相關(guān)功能的藥物研發(fā)仍處于早期階段，科研人員主要探索如何通過調(diào)節(jié)它的活性來改善血管相關(guān)疾病的治療，比如嘗試開發(fā)能增強(qiáng)它在缺血組織中作用的化合物，但這些研究尚未進(jìn)入臨床應(yīng)用環(huán)節(jié)。
熱銷產(chǎn)品
Recombinant Human Slit homolog 3 protein (SLIT3), partial (CSB-EP021769HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
SLIT3 Antibody (CSB-PA021769LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA021769LA01HU at dilution of 1:100
Human Slit homolog 3 protein(SLIT3) ELISA kit (CSB-EL021769HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL021769HU
規(guī)格：96T/48T
靈敏度：0.039 ng/mL
檢測(cè)范圍：0.156 ng/mL-10 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
SLIT3 Antibodies
SLIT3 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA050101 | SLIT3 Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-PA270713 | SLIT3 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA529294 | SLIT3 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA021769LA01HU | SLIT3 Antibody | Human | ELISA, IHC |
| CSB-PA021769LB01HU | SLIT3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA021769LC01HU | SLIT3 Antibody, FITC conjugated | Human | |
| CSB-PA021769LD01HU | SLIT3 Antibody, Biotin conjugated | Human | ELISA |
SLIT3 Proteins
SLIT3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP021769HU CSB-BP021769HU CSB-MP021769HU CSB-EP021769HU-B |
Recombinant Human Slit homolog 3 protein (SLIT3), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP021769HU | Recombinant Human Slit homolog 3 protein (SLIT3), partial | E.coli |
SLIT3 ELISA Kit
SLIT3 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL021769HU | Human Slit homolog 3 protein(SLIT3) ELISA kit | serum, plasma, cell culture supernates | 0.039 ng/mL |
