SLC39A6 (Solute Carrier Family 39 Member 6)是一種轉(zhuǎn)運(yùn)蛋白，負(fù)責(zé)將錳、鐵和鋅等離子從細(xì)胞外膜運(yùn)輸?shù)郊?xì)胞內(nèi)。它在人體中廣泛表達(dá)，尤其在腦組織中表達(dá)水平較高。SLC39A6參與許多生理和病理過(guò)程，包括神經(jīng)發(fā)育、免疫調(diào)節(jié)、細(xì)胞凋亡和代謝調(diào)節(jié)等。 近年來(lái)的研究發(fā)現(xiàn)，SLC39A6在某些癌癥中的表達(dá)水平異常，如乳腺癌、結(jié)腸癌、胃癌和前列腺癌等。SLC39A6的過(guò)度表達(dá)被認(rèn)為與某些癌癥的發(fā)生和發(fā)展有關(guān)，如通過(guò)促進(jìn)癌細(xì)胞增殖和轉(zhuǎn)移。因此，SLC39A6成為了一個(gè)重要的癌癥靶點(diǎn)，可以通過(guò)調(diào)節(jié)SLC39A6的表達(dá)和活性，以開(kāi)發(fā)新的治療癌癥的策略。此外，SLC39A6也被認(rèn)為是神經(jīng)退行性疾病的潛在治療靶點(diǎn)。

更多SLC39A6相關(guān)閱讀：鋅離子轉(zhuǎn)運(yùn)蛋白，抗體偶聯(lián)藥物ADC新晉靶點(diǎn)！

熱銷(xiāo)產(chǎn)品

Recombinant Human SLC39A6, partial (Active) (CSB-BP621669HU1)

驗(yàn)證數(shù)據(jù)

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human SLC39A6 at 1 μg/ml can bind Anti-SLC39A6 recombinant antibody (CSB-RA621669MA1HU), the EC₅₀ is 0.6873-0.9010 ng/mL.

● SLC39A6 Recombinant Monoclonal Antibody CSB-RA621669MA1HU

驗(yàn)證數(shù)據(jù)

ELISA

The Binding Activity of SLC39A6 with anti-SLC39A6 antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human SLC39A6(CSB-BP621669HU) at 1 μg/ml can bind Anti-SLC39A6-1 recombinant antibody, the EC₅₀ is 0.6873-0.9010 ng/mL.