SLC38A2
SLC38A2，全稱溶質(zhì)載體家族38成員2，是一種氨基酸轉(zhuǎn)運(yùn)蛋白，常見別名為谷氨酰胺轉(zhuǎn)運(yùn)蛋白SNAT2。該蛋白主要功能是介導(dǎo)谷氨酰胺等氨基酸的跨膜轉(zhuǎn)運(yùn)，參與細(xì)胞內(nèi)谷氨酰胺代謝的調(diào)控。SLC38A2在多種生理和病理過程中發(fā)揮重要作用，如腫瘤細(xì)胞的代謝重編程、免疫細(xì)胞的活化以及血壓的調(diào)控等。研究表明，SLC38A2在多種癌癥中異常表達(dá)，與腫瘤的侵襲、轉(zhuǎn)移和免疫抑制密切相關(guān)，因此被視為潛在的腫瘤診斷標(biāo)志物和治療靶點(diǎn)。此外，SLC38A2還與高血壓的發(fā)生發(fā)展有關(guān)，其在血管內(nèi)皮細(xì)胞中的表達(dá)上調(diào)可導(dǎo)致血壓升高?；赟LC38A2的這些特性，已有多種靶向該蛋白的藥物正在進(jìn)行研發(fā)，以期用于癌癥和高血壓的治療。
熱銷產(chǎn)品
SLC38A2 Antibody (CSB-PA847210LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: A431 whole cell lysate(30μg), HepG2 whole cell lysate(30μg), BxPC-3 whole cell lysate(30μg), PC-3 whole cell lysate(30μg), Hela whole cell lysate(30μg), A549 whole cell lysate(30μg),MCF7 whole cell lysate(30μg),Mouse Brain tissue lysate(30μg)
All lanes: SLC38A2 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/40000 dilution
Predicted band size: 57,46 kDa
Observed band size: 57 kDa
Exposure time: 120s
Immunofluorescence staining of A431 cell with CSB-PA847210LA01HU at 1:30, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunofluorescence staining of A431 cell with 5% goat serum, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
SLC38A2 Antibodies
SLC38A2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA030122 | SLC38A2 Antibody | Human | WB, ELISA |
| CSB-PA847210LA01HU | SLC38A2 Antibody | Human, Mouse | ELISA, WB, IF |
| CSB-PA847210LD01HU | SLC38A2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA847210LC01HU | SLC38A2 Antibody, FITC conjugated | Human | |
| CSB-PA847210LB01HU | SLC38A2 Antibody, HRP conjugated | Human | ELISA |
SLC38A2 Proteins
SLC38A2 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP021617BO CSB-EP021617BO CSB-BP021617BO CSB-MP021617BO CSB-EP021617BO-B |
Recombinant Bovine Sodium-coupled neutral amino acid transporter 2 (SLC38A2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC38A2 Proteins for Pan paniscus (Pygmy chimpanzee) (Bonobo)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP021617EQU CSB-EP021617EQU CSB-BP021617EQU CSB-MP021617EQU CSB-EP021617EQU-B |
Recombinant Pan paniscus Sodium-coupled neutral amino acid transporter 2 (SLC38A2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC38A2 Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP691664CH CSB-EP691664CH CSB-BP691664CH CSB-MP691664CH CSB-EP691664CH-B |
Recombinant Chicken Sodium-coupled neutral amino acid transporter 2 (SLC38A2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC38A2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP716323DIL CSB-EP716323DIL CSB-BP716323DIL CSB-MP716323DIL CSB-EP716323DIL-B |
Recombinant Danio rerio Sodium-coupled neutral amino acid transporter 2 (slc38a2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC38A2 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP730371XBF CSB-EP730371XBF CSB-BP730371XBF CSB-MP730371XBF CSB-EP730371XBF-B |
Recombinant Xenopus tropicalis Sodium-coupled neutral amino acid transporter 2 (slc38a2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC38A2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP804500MO CSB-EP804500MO CSB-BP804500MO CSB-MP804500MO CSB-EP804500MO-B |
Recombinant Mouse Sodium-coupled neutral amino acid transporter 2 (Slc38a2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC38A2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP847210HU CSB-EP847210HU CSB-BP847210HU CSB-MP847210HU CSB-EP847210HU-B |
Recombinant Human Sodium-coupled neutral amino acid transporter 2 (SLC38A2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC38A2 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP864308RA CSB-EP864308RA CSB-BP864308RA CSB-MP864308RA CSB-EP864308RA-B |
Recombinant Rat Sodium-coupled neutral amino acid transporter 2 (Slc38a2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
