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SF3B1

Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. Together with other U2 snRNP complex components may also play a role in the selective processing of microRNAs (miRNAs) from the long primary miRNA transcript, pri-miR-17-92 (By similarity). May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

SF3B1 Antibodies

SF3B1 for Homo sapiens (Human)

SF3B1 Proteins

SF3B1 Proteins for Homo sapiens (Human)

SF3B1 Proteins for Xenopus laevis (African clawed frog)

SF3B1 Proteins for Mus musculus (Mouse)



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