RIGI
RIGI，即維甲酸誘導(dǎo)基因I受體，別名DDX58、RLR-1等。它是一種細(xì)胞質(zhì)中的RNA解旋酶，屬于固有免疫的模式識(shí)別受體。RIG-I能夠結(jié)合病原相關(guān)分子模式及RNA配體識(shí)別非自身的病毒RNA，激活RIG-I信號(hào)通路，促進(jìn)細(xì)胞因子產(chǎn)生，發(fā)揮抗病毒效應(yīng)。RIG-I樣受體（RLRs）是關(guān)鍵的病毒感染感應(yīng)器，介導(dǎo)I型干擾素和其他基因的轉(zhuǎn)錄誘導(dǎo)，共同建立抗病毒宿主反應(yīng)。RIG-I在細(xì)胞內(nèi)的活性受到多種調(diào)控機(jī)制的控制，包括與RIG-I相互作用的蛋白質(zhì)、翻譯后修飾和非編碼RNAs。RIG-I在病毒感染、惡性腫瘤和自身免疫疾病中的作用，以及其在這些疾病中的調(diào)控機(jī)制，為病毒感染的控制和免疫調(diào)節(jié)治療提供了新的思路和方向。
熱銷產(chǎn)品
Recombinant?Human?Antiviral?innate?immune?response?receptor?RIG-I (RIGI), partial (CSB-EP006638HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
RIGI Antibodies
RIGI for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA006638LA01HU | DDX58 Antibody | Human | ELISA |
| CSB-PA006638GA01HU | DDX58 Antibody | Human | ELISA,WB,IF |
| CSB-PA695560 | DDX58 Antibody | Human | ELISA,WB,IHC |
| CSB-PA652501 | DDX58 Antibody | Human | ELISA,WB |
| CSB-RA207378A0HU | DDX58 Recombinant Monoclonal Antibody | Human | ELISA, IHC |
RIGI Proteins
RIGI Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP006638HU CSB-BP006638HU CSB-MP006638HU CSB-EP006638HU-B |
Recombinant?Human?Antiviral?innate?immune?response?receptor?RIG-I (RIGI), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP006638HU | Recombinant?Human?Antiviral?innate?immune?response?receptor?RIG-I (RIGI), partial | E.coli |
