PTGES3
PTGES3,全稱為前列腺素E合酶3,常用別名包括p23。它是一種多功能蛋白,常與熱休克蛋白90形成復(fù)合物,在細(xì)胞內(nèi)協(xié)助多種關(guān)鍵蛋白維持正確構(gòu)象,保障它們正常發(fā)揮生理功能。PTGES3異常表達(dá)和多種癌癥關(guān)聯(lián)緊密,比如乳腺癌、肺癌患者體內(nèi)它的含量往往升高,可能促進(jìn)腫瘤細(xì)胞生長與擴(kuò)散;此外,它在部分炎癥性疾病中也可能起到作用,影響病情進(jìn)展。目前針對該蛋白的藥物研發(fā)處于早期階段,已有一些小分子化合物被發(fā)現(xiàn)能抑制其功能,這些化合物有望成為新型抗癌或抗炎藥物的候選,不過仍需更多臨床前研究來驗證其有效性與安全性。整體來看,它是一個具有潛在臨床價值的靶點,相關(guān)研究正在逐步深入。
熱銷產(chǎn)品
Recombinant Human Prostaglandin E synthase 3 (PTGES3) (CSB-EP613587HU)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
PTGES3 Recombinant Monoclonal Antibody (CSB-RA150881A0HU)
驗證數(shù)據(jù)
Flow cytometric analysis of Prostaglandin E synthase 3 expression in HepG2 cells using Prostaglandin E synthase 3 antibody. Green, isotype control; red, Prostaglandin E synthase 3.
Immunocytochemical staining of HepG2 cells with Prostaglandin E synthase 3 antibody. Nuclei were stained blue with DAPI; Prostaglandin E synthase 3 was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: High. Scale bar, 20 μm.
Western blotting analysis using prostaglandin E synthase 3 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with prostaglandin E synthase 3 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
PTGES3 Antibodies
PTGES3 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA018978GA01HU | PTGES3 Antibody | Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA613587ESR2HU | PTGES3 Antibody | Human | ELISA |
| CSB-PA003624 | PTGES3 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA006697 | Phospho-PTGES3 (S113) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA560159 | PTGES3 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA187176 | PTGES3 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-RA150881A0HU | PTGES3 Recombinant Monoclonal Antibody | Human, Mouse, Rat | ELISA, WB, FC, ICC |
PTGES3 Proteins
PTGES3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-BP613587HU CSB-MP613587HU CSB-EP613587HU-B |
Recombinant Human Prostaglandin E synthase 3 (PTGES3) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP613587HU | Recombinant Human Prostaglandin E synthase 3 (PTGES3) | E.coli |
| CSB-YP613587HUb0 | Recombinant Human Prostaglandin E synthase 3 (PTGES3) | Yeast |
| CSB-YP613587HU | Recombinant Human Prostaglandin E synthase 3 (PTGES3) | Yeast |






