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PSIP1

PSIP1,全稱為PC4 and SFRS1 interacting protein 1,常見(jiàn)別名包括DFS70、LEDGF、p52、p75等。該蛋白在細(xì)胞核內(nèi)發(fā)揮重要作用,與多種細(xì)胞過(guò)程相關(guān)。PSIP1蛋白通過(guò)與其他蛋白相互作用,參與基因轉(zhuǎn)錄調(diào)控、DNA修復(fù)和病毒復(fù)制等過(guò)程。研究表明,PSIP1蛋白與HIV-1病毒復(fù)制密切相關(guān),能夠促進(jìn)HIV-1整合酶與染色質(zhì)的結(jié)合,從而影響病毒的復(fù)制和感染。此外,PSIP1蛋白還與某些疾病的發(fā)生發(fā)展有關(guān),如急性髓系白血病、HIV感染、斑禿等。目前,針對(duì)PSIP1蛋白的藥物研發(fā)正在積極開(kāi)展,旨在開(kāi)發(fā)出能夠抑制其功能的小分子化合物,用于治療相關(guān)疾病。

熱銷產(chǎn)品

Recombinant Human PC4 and SFRS1-interacting protein (PSIP1) (CSB-EP018860HU)

驗(yàn)證數(shù)據(jù)

CSB-EP018860HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-EP018860HU

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP018860HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) PSIP1.

CSB-EP018860HU

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP018860HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) PSIP1.

PSIP1 Proteins

PSIP1 Proteins for Homo sapiens (Human)



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