PRMT3
PRMT3，即蛋白質(zhì)精氨酸甲基轉(zhuǎn)移酶3，別名ProteinArginineMethyltransferase3。它是一種由人類基因組編碼的酶，屬于蛋白質(zhì)精氨酸甲基轉(zhuǎn)移酶家族成員之一。PRMT3的作用機制主要是催化甲基基團從S-腺苷甲硫氨酸(SAM)轉(zhuǎn)移到蛋白質(zhì)精氨酸殘基上，形成單甲基化(MMA)和非對稱二甲基化(ADMA)修飾。這種甲基化修飾能夠調(diào)控多種蛋白質(zhì)的功能，包括轉(zhuǎn)錄因子、核糖體蛋白和信號轉(zhuǎn)導分子。PRMT3參與調(diào)控細胞生長、增殖、分化和基因表達等重要生物學過程。異常的PRMT3表達或活性與腫瘤、二型糖尿病等疾病的發(fā)生發(fā)展密切相關(guān)。PRMT3通過精氨酸甲基化修飾相應的底物控制著許多重要的細胞生物學過程。
熱銷產(chǎn)品
PRMT3 Antibody (CSB-PA018733LA01HU)
驗證數(shù)據(jù)
Western blot
All lanes: PRMT3 antibody at 7μg/ml + MCF-7 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 60, 53 kDa
Observed band size: 53 kDa
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA018733LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human glioma using CSB-PA018733LA01HU at dilution of 1:100
Immunofluorescent analysis of MCF-7 cells using CSB-PA018733LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
PRMT3 Antibodies
PRMT3 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA018733GA01HU | PRMT3 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA948631 | PRMT3 Antibody | Human | ELISA,IHC |
| CSB-PA018733LA01HU | PRMT3 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA018733LB01HU | PRMT3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA018733LC01HU | PRMT3 Antibody, FITC conjugated | Human | |
| CSB-PA018733LD01HU | PRMT3 Antibody, Biotin conjugated | Human | ELISA |
PRMT3 Proteins
PRMT3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP018733HU CSB-EP018733HU CSB-BP018733HU CSB-MP018733HU CSB-EP018733HU-B |
Recombinant Human Protein arginine N-methyltransferase 3 (PRMT3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
