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PRKD1

Serine/threonine-protein kinase D1 is a protein in humans that is encoded by PRKD1 gene. Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of MAPK8/JNK1 and Ras signaling, Golgi membrane integrity and trafficking, cell survival through NF-kappa-B activation, cell migration, cell differentiation by mediating HDAC7 nuclear export, cell proliferation via MAPK1/3 (ERK1/2) signaling, and plays a role in cardiac hypertrophy, VEGFA-induced angiogenesis, genotoxic-induced apoptosis and flagellin-stimulated inflammatory response. Phosphorylates the epidermal growth factor receptor (EGFR) on dual threonine residues, which leads to the suppression of epidermal growth factor (EGF)-induced MAPK8/JNK1 activation and subsequent JUN phosphorylation.

PRKD1 Antibodies

PRKD1 for Homo sapiens (Human)

PRKD1 Proteins

PRKD1 Proteins for Homo sapiens (Human)

PRKD1 Proteins for Mus musculus (Mouse)

PRKD1 Proteins for Rattus norvegicus (Rat)



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