PPP1R3B
PPP1R3B，全稱為protein phosphatase 1 regulatory subunit 3B，常見別名包括GL、PTG、PPP1R4。該蛋白主要在肝臟和骨骼肌組織中表達(dá)，參與調(diào)節(jié)糖原合成，對維持血糖穩(wěn)態(tài)至關(guān)重要。研究表明，PPP1R3B基因的變異與多種代謝特征和肝臟相關(guān)疾病相關(guān)，但其具體作用機(jī)制尚未完全闡明。PPP1R3B蛋白與糖原代謝密切相關(guān)，其表達(dá)水平受胰島素信號通路調(diào)控。在肝臟中，PPP1R3B蛋白通過與PP1C磷酸酶結(jié)合，促進(jìn)糖原合成。此外，PPP1R3B蛋白還參與調(diào)節(jié)脂質(zhì)代謝和能量平衡。相關(guān)研究表明，PPP1R3B蛋白的表達(dá)水平與動脈粥樣硬化、代謝綜合征等疾病相關(guān)。目前，針對PPP1R3B蛋白的藥物研發(fā)尚處于早期階段，但已有研究提示其可能是治療糖尿病、脂肪肝等代謝性疾病的潛在靶點。
熱銷產(chǎn)品
PPP1R3B Antibody (CSB-PA769802LA01HU)
驗證數(shù)據(jù)
Western blot
All lanes: PPP1R3B antibody at 6µg/ml + Mouse liver tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 33 kDa
Observed band size: 33 kDa
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA769802LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA769802LA01HU at dilution of 1:100
Western Blot
Positive WB detected in: Rat heart tissue
All lanes: PPP1R3B antibody at 2.5µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 33 kDa
Observed band size: 33 kDa
PPP1R3B Antibodies
PPP1R3B for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA769802LA01HU | PPP1R3B Antibody | Human, Mouse, Rat | ELISA, WB, IHC |
| CSB-PA769802LB01HU | PPP1R3B Antibody, HRP conjugated | Human | ELISA |
| CSB-PA769802LD01HU | PPP1R3B Antibody, Biotin conjugated | Human | ELISA |
PPP1R3B Proteins
PPP1R3B Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP018548BO CSB-EP018548BO CSB-BP018548BO CSB-MP018548BO CSB-EP018548BO-B |
Recombinant Bovine Protein phosphatase 1 regulatory subunit 3B (PPP1R3B) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PPP1R3B Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP634708XBF CSB-EP634708XBF CSB-BP634708XBF CSB-MP634708XBF CSB-EP634708XBF-B |
Recombinant Xenopus tropicalis Protein phosphatase 1 regulatory subunit 3B (ppp1r3b) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PPP1R3B Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP760801RA CSB-EP760801RA CSB-BP760801RA CSB-MP760801RA CSB-EP760801RA-B |
Recombinant Rat Protein phosphatase 1 regulatory subunit 3B (Ppp1r3b) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PPP1R3B Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP769802HU CSB-EP769802HU CSB-BP769802HU CSB-MP769802HU CSB-EP769802HU-B |
Recombinant Human Protein phosphatase 1 regulatory subunit 3B (PPP1R3B) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PPP1R3B Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP773666DIL CSB-EP773666DIL CSB-BP773666DIL CSB-MP773666DIL CSB-EP773666DIL-B |
Recombinant Danio rerio Protein phosphatase 1 regulatory subunit 3B (ppp1r3b) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PPP1R3B Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP804922MO CSB-EP804922MO CSB-BP804922MO CSB-MP804922MO CSB-EP804922MO-B |
Recombinant Mouse Protein phosphatase 1 regulatory subunit 3B (Ppp1r3b) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
