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PPP1R15A

Protein phosphatase 1 regulatory subunit 15A is a protein in humans that is encoded by PPP1R15A gene. Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.

PPP1R15A Antibodies

PPP1R15A for Homo sapiens (Human)

PPP1R15A Proteins

PPP1R15A Proteins for Mus musculus (Mouse)

PPP1R15A Proteins for Homo sapiens (Human)

PPP1R15A Proteins for Bos taurus (Bovine)

PPP1R15A Proteins for Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster)

PPP1R15A Proteins for Rattus norvegicus (Rat)



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