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PLCE1

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 is a protein in humans that is encoded by PLCE1 gene. The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. PLCE1 is a bifunctional enzyme which also regulates small GTPases of the Ras superfamily through its Ras guanine-exchange factor (RasGEF) activity. As an effector of heterotrimeric and small G-protein, it may play a role in cell survival, cell growth, actin organization and T-cell activation.

PLCE1 Proteins

PLCE1 Proteins for Mus musculus (Mouse)

PLCE1 Proteins for Rattus norvegicus (Rat)

PLCE1 Proteins for Homo sapiens (Human)



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