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PIK3C2A

Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha is a protein in humans that is encoded by PIK3C2A gene. Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers. Has a role in several intracellular trafficking events. Functions in insulin signaling and secretion. Required for translocation of the glucose transporter SLC2A4/GLUT4 to the plasma membrane and glucose uptake in response to insulin-mediated RHOQ activation. Regulates insulin secretion through two different mechanisms

PIK3C2A Proteins

PIK3C2A Proteins for Homo sapiens (Human)

PIK3C2A Proteins for Pongo abelii (Sumatran orangutan)

PIK3C2A Proteins for Mus musculus (Mouse)



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