PEMT
PEMT，全稱為磷脂酰乙醇胺N-甲基轉(zhuǎn)移酶，有時也被簡稱為磷脂甲基轉(zhuǎn)移酶。它主要在肝臟組織中活躍，參與體內(nèi)脂質(zhì)相關的生理過程，能促進關鍵磷脂（磷脂酰膽堿）的生成。這種磷脂是細胞膜的核心組成部分，保障細胞結(jié)構(gòu)穩(wěn)定與功能正常，還和脂蛋白的合成、運輸密切相關，影響血脂的代謝平衡。
PEMT功能變化可能與多種疾病相關：非酒精性脂肪肝患者中常觀察到其活性異常，伴隨肝臟脂質(zhì)堆積；它還可能通過血脂代謝間接影響動脈粥樣硬化的發(fā)生風險。目前針對它的藥物研發(fā)處于早期階段，部分候選化合物在動物實驗里能調(diào)節(jié)其功能，為代謝性肝病等疾病的治療提供新方向。
熱銷產(chǎn)品
PEMT Antibody (CSB-PA017780LA01HU)
驗證數(shù)據(jù)
Western Blot
Positive WB detected in: SH-SY5Y whole cell lysate
All lanes: PEMT antibody at 2.8µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 23, 26, 25 kDa
Observed band size: 23 kDa
Immunofluorescent analysis of A549 cells using CSB-PA017780LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
PEMT Antibodies
PEMT for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA017780LA01HU | PEMT Antibody | Human | ELISA, WB, IF |
| CSB-PA017780LB01HU | PEMT Antibody, HRP conjugated | Human | ELISA |
| CSB-PA017780LC01HU | PEMT Antibody, FITC conjugated | Human | |
| CSB-PA017780LD01HU | PEMT Antibody, Biotin conjugated | Human | ELISA |
PEMT Proteins
PEMT Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP017780HU1 CSB-EP017780HU1 CSB-BP017780HU1 CSB-MP017780HU1 CSB-EP017780HU1-B |
Recombinant Human Phosphatidylethanolamine N-methyltransferase (PEMT), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF017780HU | Recombinant Human Phosphatidylethanolamine N-methyltransferase (PEMT) | in vitro E.coli expression system |
