OPA1
OPA，即視神經(jīng)萎縮蛋白1，別名OpticAtrophyType1。它是由人類(lèi)OPA1基因編碼的蛋白，主要在線粒體內(nèi)膜上發(fā)揮作用。OPA1的作用機(jī)制包括調(diào)控線粒體的融合過(guò)程，維持線粒體形態(tài)和功能，以及參與線粒體呼吸鏈超級(jí)復(fù)合物的組裝和線粒體嵴的重塑。OPA1對(duì)維持細(xì)胞能量代謝、細(xì)胞死亡、增殖以及基因表達(dá)調(diào)控具有重要作用。OPA1的異常與多種疾病相關(guān)，尤其是與視神經(jīng)萎縮（ADOA）和更廣泛的神經(jīng)系統(tǒng)癥狀。
熱銷(xiāo)產(chǎn)品
OPA1 Antibody (CSB-PA016340LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate, K562 whole cell lysate, Mouse heart tissue
All lanes: OPA1 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 112, 116 kDa
Observed band size: 112 kDa
OPA1 Antibodies
OPA1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA016340LA01HU | OPA1 Antibody | Human, Mouse | ELISA, WB |
| CSB-PA016340LB01HU | OPA1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA016340LC01HU | OPA1 Antibody, FITC conjugated | Human | |
| CSB-PA016340HA01HU | OPA1 Antibody | Human | ELISA, IHC |
| CSB-PA016340HB01HU | OPA1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA016340HC01HU | OPA1 Antibody, FITC conjugated | Human | |
| CSB-PA016340HD01HU | OPA1 Antibody, Biotin conjugated | Human | ELISA |
OPA1 Proteins
OPA1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP016340HU1 CSB-EP016340HU1 CSB-BP016340HU1 CSB-MP016340HU1 CSB-EP016340HU1-B |
Recombinant Human Dynamin-like 120 kDa protein, mitochondrial (OPA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF016340HU | Recombinant Human Dynamin-like 120 kDa protein, mitochondrial (OPA1) | in vitro E.coli expression system |
