ODC
ODC（鳥(niǎo)氨酸脫羧酶）是一種關(guān)鍵酶，它催化鳥(niǎo)氨酸脫羧生成腐胺，這是多胺合成的重要步驟。ODC由461個(gè)氨基酸組成，形成同源二聚體結(jié)構(gòu)，并在細(xì)胞內(nèi)以單體和二聚體形式迅速轉(zhuǎn)換。作為細(xì)胞生長(zhǎng)所必需的酶，ODC通過(guò)產(chǎn)生多胺來(lái)穩(wěn)定新合成的DNA，對(duì)DNA結(jié)構(gòu)穩(wěn)定、DNA雙鏈斷裂修復(fù)以及抗氧化等方面都具有重要作用。盡管ODC本身不直接參與特定的信號(hào)通路，但其在細(xì)胞生長(zhǎng)和多胺合成中的核心作用可能對(duì)某些信號(hào)通路產(chǎn)生間接影響，如通過(guò)調(diào)控Akt/GSK3β/β-catenin等信號(hào)通路影響肝癌細(xì)胞的增殖、侵襲和遷移等過(guò)程。
熱銷產(chǎn)品
Recombinant Human Ornithine decarboxylase (ODC1) (CSB-EP016269HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP016269HU could indicate that this peptide derived from E.coli-expressed Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2) ODC1 .
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP016269HU could indicate that this peptide derived from E.coli-expressed Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2) ODC1 .
ODC Antibodies
ODC for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA00535A0Rb | ODC1 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA016269GA01HU | ODC1 Antibody | Human,Mouse,Rat | ELISA,IF |
| CSB-PA00535D0Rb | ODC1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA546739 | ODC1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA818178 | ODC1 Antibody | Human,Mouse,Rat | ELISA,IHC |
ODC Proteins
ODC Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP016269HU CSB-BP016269HU CSB-MP016269HU CSB-EP016269HU-B |
Recombinant Human Ornithine decarboxylase (ODC1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP016269HU | Recombinant Human Ornithine decarboxylase (ODC1) | E.coli |
