Nr1h4
Nr1h4，全稱為法尼醇X受體，也常被叫做膽汁酸受體。它就像身體里的“代謝小管家”，主要在肝臟和腸道中忙碌，幫忙把控膽汁酸的生成與循環(huán)——膽汁酸不僅能幫我們消化脂肪，還能維持代謝系統(tǒng)的穩(wěn)定。Nr1h4功能異常，可能會引發(fā)膽汁淤積、脂肪肝等肝臟問題，甚至和某些腸道炎癥、代謝紊亂沾上邊。
目前針對Nr1h4的藥物研發(fā)已有實(shí)際成果，比如奧貝膽酸就是專門激活該蛋白的藥物，已獲批用于治療原發(fā)性膽汁性膽管炎，能有效改善患者肝功能，減輕不適癥狀。此外，還有不少在研藥物瞄準(zhǔn)這個(gè)蛋白，希望能用于非酒精性脂肪肝等代謝類疾病，為更多患者帶來治療新希望。
熱銷產(chǎn)品
Recombinant Human Bile acid receptor (NR1H4) (CSB-EP839406HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP839406HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) NR1H4.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP839406HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) NR1H4.
NR1H4 Antibody (CSB-PA839406LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: HEK293 whole cell lysate
All lanes: NR1H4 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 56, 55, 49 kDa
Observed band size: 56 kDa
Nr1h4 Antibodies
Nr1h4 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA839406LA01HU | NR1H4 Antibody | Human | ELISA, WB |
Nr1h4 Proteins
Nr1h4 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP839406HU CSB-BP839406HU CSB-MP839406HU CSB-EP839406HU-B |
Recombinant Human Bile acid receptor (NR1H4) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP839406HU | Recombinant Human Bile acid receptor (NR1H4) | E.coli |
