NRAS
NRAS，即神經(jīng)母細(xì)胞瘤RAS病毒癌基因同源物。別名N-ras、NRAS1。NRAS基因編碼一種GTP結(jié)合蛋白，在細(xì)胞信號(hào)傳導(dǎo)中起著分子開(kāi)關(guān)的作用。它通過(guò)與GTP或GDP結(jié)合來(lái)循環(huán)激活和失活狀態(tài)，控制細(xì)胞生長(zhǎng)、分化和凋亡。NRAS的作用機(jī)制涉及RAS/RAF/MEK/ERK信號(hào)通路的激活，該通路控制基因轉(zhuǎn)錄活動(dòng)和細(xì)胞周期，與細(xì)胞增殖相關(guān)。NRAS基因突變可導(dǎo)致蛋白持續(xù)激活，從而促進(jìn)腫瘤的發(fā)生和發(fā)展，如黑色素瘤、結(jié)直腸癌、非小細(xì)胞肺癌等。
熱銷產(chǎn)品
Recombinant Human GTPase NRas (NRAS) (CSB-EP016070HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
NRAS Antibody (CSB-PA016070LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA016070LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA016070LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
NRAS Antibodies
NRAS for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA052500 | NRAS Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA981790 | NRAS Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA016070LA01HU | NRAS Antibody | Human | ELISA, IHC, IF |
| CSB-PA016070LB01HU | NRAS Antibody, HRP conjugated | Human | ELISA |
| CSB-PA016070LC01HU | NRAS Antibody, FITC conjugated | Human | |
| CSB-PA016070LD01HU | NRAS Antibody, Biotin conjugated | Human | ELISA |
NRAS Proteins
NRAS Proteins for Cavia porcellus (Guinea pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP016070GU CSB-EP016070GU CSB-BP016070GU CSB-MP016070GU CSB-EP016070GU-B |
Recombinant Guinea pig GTPase NRas (NRAS) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NRAS Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP016070MO CSB-EP016070MO CSB-BP016070MO CSB-MP016070MO CSB-EP016070MO-B |
Recombinant Mouse GTPase NRas (Nras) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NRAS Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP016070HU CSB-BP016070HU CSB-EP016070HU-B |
Recombinant Human GTPase NRas (NRAS) | Yeast Baculovirus In Vivo Biotinylation in E.coli |
| CSB-EP016070HU | Recombinant Human GTPase NRas (NRAS) | E.coli |
NRAS Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP016070DIL CSB-EP016070DIL CSB-BP016070DIL CSB-MP016070DIL CSB-EP016070DIL-B |
Recombinant Danio rerio GTPase NRas (nras) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NRAS Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP645764PI CSB-EP645764PI CSB-BP645764PI CSB-MP645764PI CSB-EP645764PI-B |
Recombinant Pig GTPase NRas (NRAS) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NRAS Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP691658CH CSB-EP691658CH CSB-BP691658CH CSB-MP691658CH CSB-EP691658CH-B |
Recombinant Chicken GTPase NRas (NRAS) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NRAS Proteins for Pongo abelii (Sumatran orangutan)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP719271PYX CSB-EP719271PYX CSB-BP719271PYX CSB-MP719271PYX CSB-EP719271PYX-B |
Recombinant Pongo abelii GTPase NRas (NRAS) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NRAS Proteins for Xenopus laevis (African clawed frog)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP835522XBE CSB-EP835522XBE CSB-BP835522XBE CSB-MP835522XBE CSB-EP835522XBE-B |
Recombinant Xenopus laevis GTPase NRas (nras) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NRAS Proteins for Monodelphis domestica (Gray short-tailed opossum)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP839215MUE CSB-EP839215MUE CSB-BP839215MUE CSB-MP839215MUE CSB-EP839215MUE-B |
Recombinant Monodelphis domestica GTPase NRas (NRAS) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
