NR4A1
NR4A1，全稱為核受體亞家族4組A成員1，常見別名包括Nur77、TR3等。作為一種轉(zhuǎn)錄調(diào)控蛋白，它能響應細胞內(nèi)外的多種信號（如氧化應激、細胞因子刺激），調(diào)整下游基因的表達，影響細胞的生長、分化與凋亡過程。
在疾病方面，NR4A1與慢性炎癥、腫瘤等病癥相關：類風濕關節(jié)炎患者的炎癥組織中，該蛋白表達異常可能推動炎癥持續(xù)；肺癌、乳腺癌等腫瘤里，其活性變化與腫瘤細胞侵襲性、耐藥性有關，作用較復雜——有時促進凋亡抑癌，有時參與腫瘤進展。目前，科研人員正研究小分子化合物調(diào)節(jié)其活性，希望開發(fā)治療炎癥或癌癥的新策略。
熱銷產(chǎn)品
Recombinant Human Nuclear receptor subfamily 4immunitygroup A member 1 (NR4A1) (CSB-EP016062HU)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
NR4A1 Antibody (CSB-PA016062ESR1HU)
驗證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA016062ESR1HU at dilution of 1:100
NR4A1 Antibodies
NR4A1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA016062GA01HU | NR4A1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA198130 | Phospho-NR4A1 (Ser351) Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA568320 | NR4A1 (Ab-351) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA016062ESR1HU | NR4A1 Antibody | Human | ELISA, IHC |
| CSB-PA003493 | NR4A1 Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
| CSB-PA009233 | Phospho-NR4A1 (S351) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA179677 | NR4A1 Antibody | Human,Mouse,Rat | ELISA,WB |
NR4A1 Proteins
NR4A1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP016062MO CSB-EP016062MO CSB-BP016062MO CSB-MP016062MO CSB-EP016062MO-B |
Recombinant Mouse Nuclear receptor subfamily 4 group A member 1 (Nr4a1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NR4A1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-BP016062HU CSB-MP016062HU CSB-EP016062HU-B |
Recombinant Human Nuclear receptor subfamily 4 group A member 1 (NR4A1) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP016062HU | Recombinant Human Nuclear receptor subfamily 4immunitygroup A member 1 (NR4A1) | E.coli |
| CSB-YP016062HU | Recombinant Human Nuclear receptor subfamily 4immunitygroup A member 1 (NR4A1) | Yeast |
NR4A1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP016062RA CSB-EP016062RA CSB-BP016062RA CSB-MP016062RA CSB-EP016062RA-B |
Recombinant Rat Nuclear receptor subfamily 4 group A member 1 (Nr4a1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NR4A1 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP016062DO CSB-EP016062DO CSB-BP016062DO CSB-MP016062DO CSB-EP016062DO-B |
Recombinant Dog Nuclear receptor subfamily 4 group A member 1 (NR4A1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NR4A1 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP611718BO CSB-EP611718BO CSB-BP611718BO CSB-MP611718BO CSB-EP611718BO-B |
Recombinant Bovine Nuclear receptor subfamily 4 group A member 1 (NR4A1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
