Musk（Muscle-Specific Kinase）是肌肉特異性酪氨酸激酶的受體，它參與了神經(jīng)沖動(dòng)傳遞到肌肉的過(guò)程。Musk作為跨膜蛋白，包含有激酶結(jié)構(gòu)域。它主要存在于神經(jīng)肌肉接頭的末梢膜上，與神經(jīng)元釋放的信號(hào)物質(zhì)乙酰膽堿結(jié)合，并在肌肉細(xì)胞內(nèi)傳遞信號(hào)。Musk蛋白的主要功能是促進(jìn)神經(jīng)沖動(dòng)在神經(jīng)肌肉接頭的傳遞。當(dāng)乙酰膽堿釋放到神經(jīng)肌肉接頭時(shí)，Musk受體會(huì)激活，并引發(fā)一系列信號(hào)傳導(dǎo)過(guò)程，最終導(dǎo)致肌肉的收縮。研究Musk蛋白有助于更深入地理解神經(jīng)肌肉接頭的功能，同時(shí)也有助于了解和治療與Musk相關(guān)的疾病，比如特定類型的Myasthenia Gravis。通過(guò)深入了解Musk在神經(jīng)肌肉連接中的作用，可以為開(kāi)發(fā)相關(guān)治療方法提供重要線索。

熱銷產(chǎn)品

Recombinant Mouse Muscle, skeletal receptor tyrosine-protein kinase (Musk),partial

驗(yàn)證數(shù)據(jù)

SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

LC-MS/MS

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP730715MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Musk.

LC-MS/MS

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP730715MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Musk.