MTCH2
MTCH2，全稱為線粒體外膜蛋白2，是一種參與細(xì)胞能量代謝的重要蛋白。它主要位于線粒體外膜，負(fù)責(zé)將細(xì)胞質(zhì)中合成的蛋白轉(zhuǎn)運(yùn)至線粒體外膜。MTCH2的常見別名包括MIMP、SLC25A50等。研究發(fā)現(xiàn)，MTCH2在多種細(xì)胞過(guò)程中發(fā)揮關(guān)鍵作用，包括細(xì)胞凋亡、線粒體功能調(diào)控等。在癌癥治療中，MTCH2成為了一個(gè)重要的靶點(diǎn)。研究表明，MTCH2在非小細(xì)胞肺癌和去勢(shì)抵抗性前列腺癌中過(guò)表達(dá)，沉默或敲除MTCH2可以抑制腫瘤細(xì)胞的生長(zhǎng)和轉(zhuǎn)移，并誘導(dǎo)細(xì)胞凋亡?；谶@一發(fā)現(xiàn)，針對(duì)MTCH2的藥物研發(fā)正在積極開展中，有望為癌癥患者帶來(lái)新的治療選擇。此外，MTCH2還與AML等疾病相關(guān)，進(jìn)一步研究其功能將為疾病治療提供新的思路。
熱銷產(chǎn)品
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA083456(MTCH2 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-5: Human testis tissue, K562 cells, PC3 cells, human liver cancer tissue, hela cells, Primary antibody: CSB-PA083456(MTCH2 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
MTCH2 Antibodies
MTCH2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA015133GA01HU | MTCH2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA083456 | MTCH2 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA897586LA01HU | MTCH2 Antibody | Human | ELISA, IHC |
| CSB-PA897586LB01HU | MTCH2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA897586LC01HU | MTCH2 Antibody, FITC conjugated | Human | |
| CSB-PA897586LD01HU | MTCH2 Antibody, Biotin conjugated | Human | ELISA |
MTCH2 Proteins
MTCH2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP897586HU1 CSB-EP897586HU1 CSB-BP897586HU1 CSB-MP897586HU1 CSB-EP897586HU1-B |
Recombinant Human Mitochondrial carrier homolog 2 (MTCH2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF897586HU | Recombinant Human Mitochondrial carrier homolog 2 (MTCH2) | in vitro E.coli expression system |
