MOG

MOG，即髓鞘少突膠質(zhì)細胞糖蛋白,別名BTN6、BTNL11、MGC26137、MOG AluA、MOG AluB等。是一種主要在中樞神經(jīng)系統(tǒng)少突膠質(zhì)細胞膜表面及髓鞘最外層表達的蛋白質(zhì)，屬于免疫球蛋白超家族成員之一。MOG抗體相關疾病（MOG-IgG associated disorders, MOGAD）是近年來新認識的免疫介導的中樞神經(jīng)系統(tǒng)炎性脫髓鞘疾病，與多發(fā)性硬化（MS）和視神經(jīng)脊髓炎譜系疾病（NMOSD）不同，它是一種獨立的疾病實體。MOGAD的發(fā)病機制可能涉及MOG特異性T濾泡輔助細胞促進B細胞分化，產(chǎn)生大量MOG-IgG，這些抗體進入中樞神經(jīng)系統(tǒng)后與MOG結合，通過補體和抗體途徑介導細胞殺傷作用，導致少突膠質(zhì)細胞損傷和脫髓鞘。MOGAD的臨床表現(xiàn)多樣，包括視神經(jīng)炎、腦膜腦炎、腦干腦炎、脊髓炎等，兒童中較成人更常見，且預后相對較好。

熱銷產(chǎn)品

Recombinant Human Myelin-oligodendrocyte glycoprotein (MOG), partial (CSB-MP619083HU)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

MOG Antibody (CSB-PA619083ESR2HU)

驗證數(shù)據(jù)

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA619083ESR2HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA619083ESR2HU at dilution of 1:100

Human Myelin-oligodendrocyte glycoprotein(MOG) ELISA kit (CSB-EL014709HU)

驗證數(shù)據(jù)

貨號：CSB-EL014709HU

規(guī)格：96T/48T

靈敏度：3.9 pg/mL

檢測范圍：15.6 pg/mL-1000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

MOG Antibody

MOG Protein

MOG ELISA Kit

MOG Antibodies

MOG for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應性	應用類型
CSB-PA014709GA01HU	MOG Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA619083ESR2HU	MOG Antibody	Human	ELISA, IHC

MOG Proteins

MOG Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP619083HU CSB-BP619083HU CSB-EP619083HU-B	Recombinant Human Myelin-oligodendrocyte glycoprotein (MOG), partial	Yeast Baculovirus In Vivo Biotinylation in E.coli
CSB-EP619083HU	Recombinant Human Myelin-oligodendrocyte glycoprotein (MOG), partial	E.coli
CSB-MP619083HU(A4)	Recombinant Human Myelin-oligodendrocyte glycoprotein (MOG)-VLPs, Fluorescent	Mammalian cell
CSB-MP619083HU	Recombinant Human Myelin-oligodendrocyte glycoprotein (MOG), partial	Mammalian cell