MMP9

MMP9，即基質(zhì)金屬蛋白酶9。它是一種在多種細胞類型中表達的酶，包括中性粒細胞、單核細胞、巨噬細胞等。MMP9的來源是人體細胞自身的基因編碼，其作用機制涉及催化細胞外基質(zhì)(extracellular matrix, ECM)成分的降解，如膠原蛋白、彈性蛋白、明膠等，對維持組織結(jié)構(gòu)和功能的動態(tài)平衡至關(guān)重要。MMP9的活性受到多種調(diào)控機制的影響，包括酶原激活、抑制因子如金屬蛋白酶組織抑制因子(TIMPs)的抑制作用。MMP9在生物學上的意義非常廣泛，它參與了多種生理和病理過程，包括組織修復(fù)、炎癥反應(yīng)、腫瘤發(fā)展和轉(zhuǎn)移等。MMP9通過降解ECM和非ECM底物，如細胞因子和生長因子，參與調(diào)節(jié)細胞增殖、遷移和凋亡等過程。在疾病狀態(tài)下，MMP9的異常表達或活性與心血管疾病、纖維化疾病、腫瘤侵襲和轉(zhuǎn)移等有關(guān)。例如，在心肌梗塞后的心臟重構(gòu)中，MMP9的活性增加與心臟功能障礙相關(guān) 。MMP9的活性還與腫瘤微環(huán)境中的血管生成和免疫逃逸有關(guān)，使其成為癌癥治療的潛在靶點。

熱銷產(chǎn)品

Recombinant Horse Matrix metalloproteinase-9 (MMP9), partial (CSB-YP3996HO)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

MMP9 Antibody (CSB-PA058909)

驗證數(shù)據(jù)

Western blot analysis of extracts from Hela cells using MMP-9 Antibody.

MMP9 Antibody

MMP9 Protein

MMP9 ELISA Kit

MMP9 Antibodies

MMP9 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA014679GA01HU	MMP9 Antibody	human	ELISA,WB,IHC
CSB-PA436677	MMP9 Antibody	Human	ELISA,WB,IHC
CSB-PA142806	MMP9 Antibody	Human	ELISA,WB,IHC
CSB-PA002676	MMP9 Antibody	Human	WB, IHC, IF, ELISA
CSB-PA005569	MMP9 Antibody	Human	WB, ELISA
CSB-PA699938	MMP9 Antibody	Human	ELISA,IHC
CSB-PA255651	MMP9 Antibody	Human	ELISA,IHC
CSB-PA563134	MMP9 Antibody	Human	ELISA,IHC
CSB-PA151401	MMP9 Antibody	Human	ELISA,WB,IHC
CSB-PA294107	MMP9 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA796774	MMP9 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-RA014679A0HU	MMP9 Recombinant Monoclonal Antibody	Human	ELISA, IHC, FC
CSB-RA014679MA1HU	MMP9 Recombinant Monoclonal Antibody	Human	ELISA, IHC

MMP9 Proteins

MMP9 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP014679HU	Recombinant Human Matrix metalloproteinase-9 (MMP9), partial	Yeast
CSB-EP014679HU CSB-BP014679HU CSB-MP014679HU CSB-EP014679HU-B	Recombinant Human Matrix metalloproteinase-9 (MMP9), partial	E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MMP9 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP014679MO CSB-EP014679MO CSB-BP014679MO CSB-MP014679MO CSB-EP014679MO-B	Recombinant Mouse Matrix metalloproteinase-9 (Mmp9)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MMP9 Proteins for Oryctolagus cuniculus (Rabbit)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP014679RB CSB-EP014679RB CSB-BP014679RB CSB-MP014679RB CSB-EP014679RB-B	Recombinant Rabbit Matrix metalloproteinase-9 (MMP9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MMP9 Proteins for Bos taurus (Bovine)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-EP014679BO CSB-BP014679BO CSB-MP014679BO CSB-EP014679BO-B	Recombinant Bovine Matrix metalloproteinase-9 (MMP9)	E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MMP9 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP014679DO	Recombinant Dog Matrix metalloproteinase-9 (MMP9)	Yeast

MMP9 Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP014679RA CSB-EP014679RA CSB-BP014679RA CSB-MP014679RA CSB-EP014679RA-B	Recombinant Rat Matrix metalloproteinase-9 (Mmp9)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MMP9 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-EP014679DO CSB-BP014679DO CSB-MP014679DO CSB-EP014679DO-B	Recombinant Dog Matrix metalloproteinase-9 (MMP9)	E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli