MMP14

MMP14，即基質金屬蛋白酶14，別名MT1-MMP。它由人類MMP14基因編碼，位于染色體12上。MMP14是一種膜型基質金屬蛋白酶，主要在細胞表面發(fā)揮作用，通過其催化活性區(qū)含有的鋅離子結合位點，對酶催化作用的發(fā)揮至關重要。MMP14的作用機制包括激活其他MMPs（如MMP2），參與細胞外基質的重塑，影響腫瘤的侵襲和轉移。MMP14參與組織發(fā)育、生殖、組織重塑等正常生理過程，同時在疾病過程中如關節(jié)炎、腫瘤轉移中發(fā)揮作用。MMP14的表達水平在多種腫瘤中上調，與腫瘤的預后密切相關，如在胰腺癌、肝癌等腫瘤中高表達與不良預后相關。此外，MMP14還參與調節(jié)免疫反應和炎癥過程。

熱銷產品

Recombinant Human Matrix metalloproteinase-14 (MMP14) (CSB-EP014661HU)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP014661HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) MMP14.

MMP14 Antibody (CSB-PA014661ESR1HU)

驗證數(shù)據(jù)

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA014661ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA014661ESR1HU at dilution of 1:100

MMP14 Antibody

MMP14 Protein

MMP14 ELISA Kit

MMP14 Antibodies

MMP14 for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA014661GA01HU	MMP14 Antibody	Human,Mouse,Rat,Zebrafish	ELISA,WB
CSB-PA12389D0Rb	MMP14 Antibody, Biotin conjugated	Human	ELISA
CSB-PA12389A0Rb	MMP14 Antibody	Human	ELISA, IHC
CSB-PA014661ESR1HU	MMP14 Antibody	Human	ELISA, IHC
CSB-PA897896	MMP14 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA000050	Cleaved-MMP14 (Y112) Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA010212	MMP14 Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA971298	MMP14 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA553918	MMP14 Antibody	Human,Mouse,Rat	ELISA,IHC

MMP14 Proteins

MMP14 Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-YP014661HU CSB-BP014661HU CSB-MP014661HU CSB-EP014661HU-B	Recombinant Human Matrix metalloproteinase-14 (MMP14), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP014661HU	Recombinant Human Matrix metalloproteinase-14 (MMP14)	E.coli
CSB-CF014661HU	Recombinant Human Matrix metalloproteinase-14 (MMP14)	in vitro E.coli expression system

MMP14 Proteins for Mus musculus (Mouse)

產品貨號	產品名稱	來源
CSB-YP014661MO1 CSB-BP014661MO1 CSB-MP014661MO1 CSB-EP014661MO1-B	Recombinant Mouse Matrix metalloproteinase-14 (Mmp14), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF014661MO	Recombinant Mouse Matrix metalloproteinase-14 (Mmp14)	in vitro E.coli expression system

MMP14 Proteins for Rattus norvegicus (Rat)

產品貨號	產品名稱	來源
CSB-YP608834RA CSB-EP608834RA CSB-BP608834RA CSB-MP608834RA CSB-EP608834RA-B	Recombinant Rat Matrix metalloproteinase-14 (Mmp14), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MMP14 Proteins for Pongo abelii (Sumatran orangutan)

產品貨號	產品名稱	來源
CSB-YP725453PYX CSB-EP725453PYX CSB-BP725453PYX CSB-MP725453PYX CSB-EP725453PYX-B	Recombinant Pongo abelii Matrix metalloproteinase-14 (MMP14), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MMP14 Proteins for Oryctolagus cuniculus (Rabbit)

產品貨號	產品名稱	來源
CSB-YP839160RB CSB-EP839160RB CSB-BP839160RB CSB-MP839160RB CSB-EP839160RB-B	Recombinant Rabbit Matrix metalloproteinase-14 (MMP14), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MMP14 Proteins for Bos taurus (Bovine)

產品貨號	產品名稱	來源
CSB-YP884395BO CSB-EP884395BO CSB-BP884395BO CSB-MP884395BO CSB-EP884395BO-B	Recombinant Bovine Matrix metalloproteinase-14 (MMP14), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MMP14 Proteins for Sus scrofa (Pig)

產品貨號	產品名稱	來源
CSB-YP896435PI CSB-EP896435PI CSB-BP896435PI CSB-MP896435PI CSB-EP896435PI-B	Recombinant Pig Matrix metalloproteinase-14 (MMP14), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli