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MIA2

MIA2,全稱為黑色素瘤抑制活性蛋白2,是一種在肝臟中高表達(dá)的分泌性蛋白,在睪丸中的表達(dá)較弱。該蛋白也被稱為天然α1微球蛋白或白介素10等。MIA2蛋白屬于MIA/OTOR家族,與MIA、OTOR和TANGO等蛋白共享一個(gè)Src同源性3 (SH3) 類結(jié)構(gòu)域。在臨床應(yīng)用中,MIA2蛋白的水平可作為診斷肝病活動(dòng)性和嚴(yán)重程度的實(shí)用標(biāo)記,尤其在患有嚴(yán)重纖維化或炎癥以及慢性肝炎的患者中,MIA2水平顯著高于其他患者。近年來,隨著對MIA2蛋白研究的深入,其在腫瘤抑制和免疫調(diào)節(jié)方面的作用也逐漸被關(guān)注。目前,針對MIA2蛋白的藥物研發(fā)正在積極推進(jìn)中,旨在開發(fā)更有效的腫瘤治療和免疫調(diào)節(jié)藥物。

熱銷產(chǎn)品

MIA2 Antibody (CSB-PA822278LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA822278LA01HU

IHC image of CSB-PA822278LA01HU diluted at 1:300 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA822278LA01HU

IHC image of CSB-PA822278LA01HU diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

MIA2 Antibodies

MIA2 for Homo sapiens (Human)

MIA2 Proteins

MIA2 Proteins for Homo sapiens (Human)



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