日本高潮视频在线观看-亚洲中文字幕永不卡-精品亚洲一区二区三区-伦理片夜夜躁狠狠躁日日躁-日本最新免费不卡二区-国产精品口爆一区二区三区-av一区二区三区高清-大鸡巴疯狂抽插小穴视频-日韩中文国产在线观看免费视频

Your Good Partner in Biology Research

MAPKAP1

Target of rapamycin complex 2 subunit MAPKAP1 is a protein in humans that is encoded by MAPKAP1 gene. Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'.

MAPKAP1 Antibodies

MAPKAP1 for Homo sapiens (Human)

MAPKAP1 Proteins

MAPKAP1 Proteins for Bos taurus (Bovine)

MAPKAP1 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

MAPKAP1 Proteins for Rattus norvegicus (Rat)

MAPKAP1 Proteins for Pongo abelii (Sumatran orangutan)

MAPKAP1 Proteins for Ovis aries (Sheep)

MAPKAP1 Proteins for Xenopus laevis (African clawed frog)

MAPKAP1 Proteins for Mus musculus (Mouse)

MAPKAP1 Proteins for Homo sapiens (Human)

MAPKAP1 Proteins for Gallus gallus (Chicken)



×