MAGEA4

MAGEA4，即黑色素瘤相關(guān)抗原A4，別名MAGE-4、MAGE-41、MAGE-X2等。MAGEA4基因?qū)儆贛AGE家族，位于人類的X號染色體上。MAGEA4的作用機制主要涉及其編碼的蛋白質(zhì)在細胞內(nèi)的表達，這些蛋白質(zhì)通常在腫瘤細胞中表達，而在正常組織中表達較低或不表達，尤其是在睪丸等免疫豁免部位。MAGEA4在腫瘤細胞中的表達可能與抑制細胞凋亡和促進腫瘤生長有關(guān)。此外，MAGEA4還可以作為免疫治療的靶點，通過激活針對MAGEA4的免疫反應(yīng)來攻擊腫瘤細胞。MAGEA4在多種腫瘤中表達，包括肺癌、卵巢癌、黑色素瘤等，其表達水平與腫瘤的侵襲性和預(yù)后密切相關(guān)，MAGEA4的檢測和靶向治療具有重要的生物學意義。

熱銷產(chǎn)品

Recombinant Human Melanoma-associated antigen 4 (MAGEA4) (Active) (CSB-MP013330HU)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human MAGEA4 at 2 μg/ml can bind anti-MAGEA4 recombinant antibody, the EC₅₀ is 30.33-43.10 ng/mL.

MAGEA4 Antibody (CSB-PA013330LA01HU)

驗證數(shù)據(jù)

Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA013330LA01HU at dilution of 1:100

MAGEA4 Antibody

MAGEA4 Protein

MAGEA4 Antibodies

MAGEA4 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA013330GA01HU	MAGEA4 Antibody	Human	ELISA,IHC
CSB-PA059198	MAGEA4 Antibody	Human	ELISA,IHC
CSB-PA179901	MAGEA4 Antibody	Human	ELISA,IHC
CSB-PA013330LA01HU	MAGEA4 Antibody	Human	ELISA, IHC
CSB-PA013330LD01HU	MAGEA4 Antibody, Biotin conjugated	Human	ELISA
CSB-PA013330LC01HU	MAGEA4 Antibody, FITC conjugated	Human
CSB-PA013330LB01HU	MAGEA4 Antibody, HRP conjugated	Human	ELISA
CSB-MA013330A0m	MAGEA4 Monoclonal Antibody	Human	ELISA, IHC, FC

MAGEA4 Proteins

MAGEA4 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP013330HU CSB-EP013330HU CSB-BP013330HU CSB-EP013330HU-B	Recombinant Human Melanoma-associated antigen 4 (MAGEA4)	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-EP013330HU(M)	Recombinant Human Melanoma-associated antigen 4 (MAGEA4)	E.coli
CSB-MP013330HU	Recombinant Human Melanoma-associated antigen 4 (MAGEA4) (Active)	Mammalian cell
CSB-EP013330HUb0	Recombinant Human Melanoma-associated antigen 4 (MAGEA4)	E.coli