LCN2

LCN2，全稱為脂質(zhì)運載蛋白2（Lipocalin-2），是一種分泌性糖蛋白，在人體內(nèi)多種組織中表達(dá)，包括肝、肺、腎、脂肪細(xì)胞、活化的中性粒細(xì)胞和巨噬細(xì)胞等。LCN2也被稱為中性粒細(xì)胞明膠酶相關(guān)脂質(zhì)運載蛋白（NGAL）、24p3、siderocalin或中性粒細(xì)胞脂質(zhì)運載蛋白（NL）。其作用機(jī)制多樣，涉及鐵的轉(zhuǎn)運、調(diào)節(jié)免疫反應(yīng)、維持鐵穩(wěn)態(tài)和促進(jìn)上皮細(xì)胞分化等多個方面。LCN2通過螯合鐵來參與先天性免疫，限制細(xì)菌的生長。它也是腎損傷的生物標(biāo)志物，在慢性腎臟病、造影劑腎病和腎移植等疾病中發(fā)揮重要作用。此外，LCN2還與神經(jīng)系統(tǒng)疾病、肝臟疾病、呼吸系統(tǒng)疾病等多種疾病相關(guān)。目前，LCN2已被用作多種疾病的生物標(biāo)志物，并在藥物研發(fā)中展現(xiàn)出巨大潛力。例如，LCN2已被用作急性腎損傷（AKI）的早期診斷工具，以及阿爾茨海默病、血管性癡呆、帕金森病等神經(jīng)系統(tǒng)疾病的潛在治療靶點。

熱銷產(chǎn)品

Recombinant Human Neutrophil gelatinase-associated lipocalin (LCN2) (Active) (CSB-AP000461HU)

驗證數(shù)據(jù)

LCN2 Monoclonal Antibody (CSB-MA068302A0m)

驗證數(shù)據(jù)

All lanes:Mouse anti-human Neutrophil gelatinase-associated lipocalin monoclonal antibody at 1μg/ml
Lane 1:NGAL transfected 293 cell lysate
Predicted band size : 22 kDa
Observed band size : 25 kDa

Immunohistochemical of paraffin-embedded human spleen organization using CSB-MA068302A0m at dilution of 1:200

Immunohistochemical of paraffin-embedded human prostate tissue using CSB-MA068302A0m at dilution of 1:200

LCN2 Antibody

LCN2 Protein

LCN2 ELISA Kit

LCN2 Antibodies

LCN2 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA06834D0Rb	LCN2 Antibody, Biotin conjugated	Human	ELISA
CSB-PA06836A0Rb	LCN2 Antibody	Human	ELISA, WB
CSB-PA06836D0Rb	LCN2 Antibody, Biotin conjugated	Human	ELISA
CSB-MA068302A0m	LCN2 Monoclonal Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA06837A0Rb	LCN2 Antibody	Human	ELISA
CSB-PA06837B0Rb	LCN2 Antibody, HRP conjugated	Human	ELISA
CSB-PA06837C0Rb	LCN2 Antibody, FITC conjugated	Human
CSB-PA06837D0Rb	LCN2 Antibody, Biotin conjugated	Human	ELISA
CSB-PA076130	LCN2 Antibody	Human	ELISA,IHC
CSB-PA171092	LCN2 Antibody	Human	ELISA,WB,IHC
CSB-PA06834A0Rb	LCN2 Antibody	Human	ELISA, WB

LCN2 for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA012816LA01RA	Lcn2 Antibody	Rat	ELISA, IHC
CSB-PA012816LB01RA	Lcn2 Antibody, HRP conjugated	Rat	ELISA
CSB-PA012816LC01RA	Lcn2 Antibody, FITC conjugated	Rat
CSB-PA012816LD01RA	Lcn2 Antibody, Biotin conjugated	Rat	ELISA

LCN2 Proteins

LCN2 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP012816MO CSB-EP012816MO CSB-BP012816MO CSB-MP012816MO CSB-EP012816MO-B	Recombinant Mouse Neutrophil gelatinase-associated lipocalin (Lcn2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

LCN2 Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP012816RA CSB-EP012816RA CSB-BP012816RA CSB-MP012816RA CSB-EP012816RA-B	Recombinant Rat Neutrophil gelatinase-associated lipocalin (Lcn2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli