KARS1
KARS1，全稱為賴氨酰-tRNA合成酶1，也被稱為賴氨酸氨酰-tRNA合成酶。該蛋白質(zhì)在細(xì)胞內(nèi)負(fù)責(zé)將賴氨酸這種氨基酸連接到對應(yīng)的tRNA分子上，是蛋白質(zhì)合成過程中的關(guān)鍵步驟。KARS1蛋白的異常變異會導(dǎo)致一系列罕見的綜合征，包括神經(jīng)系統(tǒng)損傷、心臟和肝臟疾病以及聽力損失。研究表明，這些變異會影響KARS1蛋白的正常功能，進(jìn)而干擾蛋白質(zhì)的合成，導(dǎo)致細(xì)胞和組織的損傷。目前，針對KARS1相關(guān)疾病的治療方法有限，主要集中在支持性治療上。然而，隨著對KARS1蛋白功能和變異的深入研究，科學(xué)家們正在探索新的治療策略，例如通過藥物調(diào)節(jié)KARS1蛋白的表達(dá)或活性，以期改善患者的癥狀和預(yù)后。
熱銷產(chǎn)品
KARS Antibody (CSB-PA04689A0Rb)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: MCF-7 whole cell lysate
All lanes: KARS antibody at 2.5µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 69, 72 kDa
Observed band size: 69 kDa
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA04689A0Rb at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA04689A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
KARS1 Antibodies
KARS1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA011986GA01HU | KARS Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA163096 | KARS Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA056745 | KARS Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA04689A0Rb | KARS Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA04689B0Rb | KARS Antibody, HRP conjugated | Human | ELISA |
| CSB-PA04689D0Rb | KARS Antibody, Biotin conjugated | Human | ELISA |
KARS1 Proteins
KARS1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP618973HU CSB-EP618973HU CSB-BP618973HU CSB-MP618973HU CSB-EP618973HU-B |
Recombinant Human Lysine--tRNA ligase (KARS) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
