IP6K2
IP6K2，全稱為肌醇六磷酸激酶2，是一種參與細(xì)胞內(nèi)信號(hào)傳導(dǎo)的重要分子。它能夠催化肌醇六磷酸（InsP6）生成焦磷酸肌醇（InsP7），進(jìn)而影響多種細(xì)胞功能。IP6K2蛋白在炎癥性結(jié)直腸癌、胃癌、食管癌等多種消化道腫瘤中異常激活，提示其可能成為跨癌種治療的靶點(diǎn)。此外，IP6K2蛋白與溶瘤病毒療法耐藥性相關(guān)，可作為預(yù)測(cè)治療效果的生物標(biāo)志物。目前，針對(duì)IP6K2蛋白的藥物研發(fā)正在積極進(jìn)行中，例如，靶向IP6K2-5-IP7軸的藥物可通過修復(fù)腸道屏障功能，阻斷炎癥與癌變的惡性循環(huán)，為癌癥治療開辟了新賽道。
熱銷產(chǎn)品
IP6K2 Antibody (CSB-PA011771ESR1HU)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: IP6K2 antibody at 3.12µg/ml + Raji whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 50, 12, 9, 21, 22, 10 kDa
Observed band size: 50 kDa
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA011771ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA011771ESR1HU at dilution of 1:100
IP6K2 Antibodies
IP6K2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA011771GA01HU | IP6K2 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA109004 | IP6K2 Antibody | Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA003056 | IP6K2 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA011771ESR1HU | IP6K2 Antibody | Human | ELISA, WB, IHC |
IP6K2 Proteins
IP6K2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011771MO CSB-EP011771MO CSB-BP011771MO CSB-MP011771MO CSB-EP011771MO-B |
Recombinant Mouse Inositol hexakisphosphate kinase 2 (Ip6k2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IP6K2 Proteins for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011771RB CSB-EP011771RB CSB-BP011771RB CSB-MP011771RB CSB-EP011771RB-B |
Recombinant Rabbit Inositol hexakisphosphate kinase 2 (IP6K2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IP6K2 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011771RA CSB-EP011771RA CSB-BP011771RA CSB-MP011771RA CSB-EP011771RA-B |
Recombinant Rat Inositol hexakisphosphate kinase 2 (Ip6k2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IP6K2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011771HU CSB-EP011771HU CSB-BP011771HU CSB-MP011771HU CSB-EP011771HU-B |
Recombinant Human Inositol hexakisphosphate kinase 2 (IP6K2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
