INHBC
INHBC，全稱為抑制素βC亞基，屬于轉(zhuǎn)化生長(zhǎng)因子β超家族成員，常被簡(jiǎn)稱為INH-βC。它多與其他亞基結(jié)合形成二聚體，在體內(nèi)參與激素分泌的平衡調(diào)控，尤其對(duì)生殖系統(tǒng)的激素調(diào)節(jié)有影響，比如作用于卵泡刺激素的釋放，維持生殖功能的正常運(yùn)轉(zhuǎn)。
INHBC表達(dá)異?？赡荜P(guān)聯(lián)多種疾病。多囊卵巢綜合征患者體內(nèi)其水平常出現(xiàn)波動(dòng)，可能干擾卵巢排卵；在卵巢癌、子宮內(nèi)膜癌等生殖系統(tǒng)腫瘤中，它的表達(dá)量也可能發(fā)生改變，與腫瘤的發(fā)生發(fā)展存在一定聯(lián)系。目前針對(duì)該蛋白的藥物研發(fā)還在早期階段，主要探索其作為疾病標(biāo)志物的潛力，以及開發(fā)靶向它的候選藥物用于相關(guān)疾病治療，但尚未有上市藥物。
熱銷產(chǎn)品
Recombinant Human Inhibin beta C chain (INHBC), partial (CSB-EP011721HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
INHBC Antibody (CSB-PA011721ESR1HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA011721ESR1HU at dilution of 1:100
INHBC Antibodies
INHBC for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA003039 | INHBC Antibody | Human | WB, IHC, ELISA |
| CSB-PA971390 | INHBC Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA011721ESR1HU | INHBC Antibody | Human | ELISA, IHC |
| CSB-PA011721ESR2HU | INHBC Antibody | Human | ELISA, WB, IHC |
INHBC Proteins
INHBC Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011721HU CSB-BP011721HU CSB-MP011721HU CSB-EP011721HU-B |
Recombinant Human Inhibin beta C chain (INHBC) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP005431HU | Recombinant Human Inhibin beta C chain (INHBC), partial (Active) | E.coli |
| CSB-AP005511HU | Recombinant Human Inhibin beta C chain (INHBC) (Active) | Mammalian cell |
| CSB-EP011721HU | Recombinant Human Inhibin beta C chain (INHBC), partial | E.coli |
| CSB-MP011721HUr10 | Recombinant Human Inhibin beta C chain (INHBC) | Mammalian cell |
INHBC Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011721MO CSB-BP011721MO CSB-EP011721MO-B |
Recombinant Mouse Inhibin beta C chain (Inhbc) | Yeast Baculovirus In Vivo Biotinylation in E.coli |
INHBC Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP896246RA CSB-EP896246RA CSB-BP896246RA CSB-EP896246RA-B |
Recombinant Rat Inhibin beta C chain (Inhbc) | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
