IL31
IL-31是一種屬于糖蛋白130 (gp130)/IL-6細胞因子家族的細胞因子，具有獨特的四螺旋束結(jié)構(gòu)。它通過與IL-31受體α（IL-31RA）和抑瘤素M受體（OSMR）組成的異源二聚體復合物結(jié)合，激活包括PI3K/AKT、JAK/STAT以及MAPK在內(nèi)的信號通路，從而在炎癥和免疫反應中發(fā)揮關鍵作用。IL-31主要由Th2細胞、肥大細胞等免疫細胞產(chǎn)生，并參與特應性皮炎、哮喘等疾病的發(fā)病機制。因此，對IL-31的結(jié)構(gòu)、信號通路與功能的深入研究，對于理解這些疾病的病理過程以及開發(fā)新的治療方法具有重要意義。
熱銷產(chǎn)品
Recombinant Human Interleukin-31 (IL31) (CSB-MP735356HU)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
IL31 Antibodies
IL31 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA930930 | IL31 Antibody | Human | ELISA,IHC |
| CSB-PA239746 | IL31 Antibody | Human | ELISA,WB,IHC |
| CSB-PA723018 | IL31 Antibody | Human | WB,ELISA |
IL31 Proteins
IL31 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP735356HU CSB-EP735356HU-B |
Recombinant Human Interleukin-31 (IL31) | Yeast In Vivo Biotinylation in E.coli |
| CSB-AP001901HU | Recombinant Human Interleukin-31 protein (IL31) | E.Coli |
| CSB-EP735356HU | Recombinant Human Interleukin-31 (IL31) | E.coli |
| CSB-BP735356HU | Recombinant Human Interleukin-31 (IL31) | Baculovirus |
| CSB-AP004631HU | Recombinant Human Interleukin-31 (IL31) (Active) | E.coli |
| CSB-MP735356HU | Recombinant Human Interleukin-31 (IL31) | Mammalian cell |
IL31 ELISA Kit
IL31 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E16999h | Human Interleukin 31(IL-31) ELISA Kit | serum, plasma, tissue homogenates. | 31.25 pg/ml. |
