IL22
IL22，即白細(xì)胞介素22，它是一種由Th17細(xì)胞、Th22細(xì)胞以及先天淋巴細(xì)胞等免疫細(xì)胞產(chǎn)生的細(xì)胞因子。IL22主要在腸道、肝、肺和皮膚等屏障組織中發(fā)揮作用。其作用機(jī)制涉及與特異性受體IL22R結(jié)合，該受體由IL22RA1和IL10RB亞基組成。結(jié)合后，IL22激活JAK/STAT信號(hào)通路，特別是STAT3的磷酸化，進(jìn)而調(diào)控靶基因的表達(dá)。這一信號(hào)通路參與調(diào)節(jié)細(xì)胞增殖、分化、組織修復(fù)以及抗微生物反應(yīng)。IL22對(duì)維持上皮細(xì)胞屏障的完整性、促進(jìn)損傷后的組織再生和調(diào)節(jié)宿主防御機(jī)制具有重要作用。它在炎癥性腸病、肝病以及皮膚疾病中的作用尤其受到關(guān)注，其調(diào)節(jié)免疫反應(yīng)和促進(jìn)組織修復(fù)的功能使其成為治療相關(guān)疾病的潛在靶點(diǎn)。
熱銷產(chǎn)品
IL22 Antibody (CSB-PA867113ESR1HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA867113ESR1HU at dilution of 1:100
Mouse Interleukin 22(IL-22) ELISA Kit (CSB-E13513m)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-E13513m
規(guī)格：96T/48T
靈敏度：0.078 ng/mL
檢測(cè)范圍：0.312 ng/mL-20 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
IL22 Antibodies
IL22 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA011635GA01HU | IL22 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA867113ESR1HU | IL22 Antibody | Human | ELISA, IHC |
| CSB-RA867113MA1HU | IL22 Recombinant Monoclonal Antibody | Human | ELISA, IHC |
IL22 Proteins
IL22 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP867113HU CSB-EP867113HU CSB-BP867113HU CSB-EP867113HU-B |
Recombinant Human Interleukin-22 (IL22) | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-AP001891HU | Recombinant Human Interleukin-22 protein (IL22) | E.Coli |
| CSB-AP004361HU | Recombinant Human Interleukin-22 (IL22), partial (Active) | E.coli |
IL22 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP872862MO CSB-EP872862MO CSB-BP872862MO CSB-MP872862MO CSB-EP872862MO-B |
Recombinant Mouse Interleukin-22 (Il22) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP003401MO | Recombinant Mouse Interleukin-22 protein (Il22) | E.Coli |
IL22 ELISA Kit
IL22 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13513m | Mouse Interleukin 22(IL-22) ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 0.078 ng/mL |
IL22 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13418h | Human Interleukin 22(IL-22) ELISA KIT | serum, plasma, tissue homogenates | 19.5 pg/ml |
| CSB-E13418h-IS | Human Interleukin 22(IL-22) ELISA KIT | serum, plasma, tissue homogenates, cell culture supernates | 0.98 pg/mL |
