IL1RL1
IL1RL1，即白細(xì)胞介素-1受體樣1，是Toll樣/白細(xì)胞介素-1受體家族的一員，其結(jié)構(gòu)包含一個(gè)細(xì)胞外配體結(jié)合域、跨膜域和細(xì)胞內(nèi)信號(hào)傳導(dǎo)域。IL1RL1主要參與由IL-33介導(dǎo)的信號(hào)通路，通過(guò)與IL-33結(jié)合觸發(fā)細(xì)胞內(nèi)信號(hào)傳導(dǎo)，如NF-κB和MAPK通路的激活，進(jìn)而在免疫調(diào)節(jié)和炎癥反應(yīng)中發(fā)揮關(guān)鍵作用。IL1RL1的激活可以促進(jìn)炎癥介質(zhì)的釋放，并促進(jìn)Th2型免疫反應(yīng)，這些功能在多種疾病如哮喘和過(guò)敏性皮炎中具有重要意義。因此，IL1RL1是一個(gè)潛在的疾病治療靶點(diǎn)。
熱銷產(chǎn)品
Recombinant Human Interleukin-1 receptor-like 1 (IL1RL1), partial (Active) (CSB-MP011626HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
①M(fèi)easured by its binding ability in a functional ELISA.Immobilized Human IL1RL1 at 2 μg/ml can bind Anti-IL1RL1 recombinant antibody(CSB-RA011626MA1HU). The EC50 is 6.366-7.698 ng/mL.
Activity
②Measured by its binding ability in a functional ELISA.Immobilized Human IL1RL1 at 2 μg/ml can bind Anti-IL1RL1 recombinant antibody(CSB-RA011626MA2HU). The EC50 is 11.85-13.96 ng/mL.
The purity of IL1RL1 was greater than 95% as determined by SEC-HPLC
Mouse Interleukin-1 receptor-like 1(IL1RL1) ELISA kit (CSB-EL011626MO)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL011626MO
規(guī)格：96T/48T
靈敏度：19.5 pg/ml
檢測(cè)范圍：78 pg/ml-5000 pg/ml
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
IL1RL1 Antibodies
IL1RL1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA011626GA01HU | IL1RL1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA07209A0Rb | IL1RL1 Antibody | Human | ELISA |
| CSB-PA550856 | IL1RL1 Antibody | Human | ELISA,WB,IHC |
| CSB-PA984274 | IL1RL1 Antibody | Human | ELISA,WB,IHC |
IL1RL1 ELISA Kit
IL1RL1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13789h | Human IL-1 Receptor Like 1(IL1RL1)ELISA Kit | serum, plasma, tissue homogenates | 11.75pg/ml |
