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HIST1H3A

HIST1H3A,全名為Histone H3.1,是一種組蛋白蛋白質(zhì)。組蛋白是染色質(zhì)的主要組成部分,負(fù)責(zé)DNA的包裝和調(diào)控基因表達(dá)。組蛋白H3是核小體的主要組成蛋白,通過(guò)與DNA結(jié)合形成核小體顆粒,進(jìn)一步組裝成染色質(zhì)。這種包裝使得DNA在細(xì)胞核內(nèi)能夠緊密地組織起來(lái),從而允許在較小的細(xì)胞核空間內(nèi)容納大量的遺傳信息。組蛋白在細(xì)胞的染色質(zhì)結(jié)構(gòu)和基因表達(dá)調(diào)控中起著重要作用。特定的組蛋白修飾可以影響染色質(zhì)的緊密程度,進(jìn)而影響基因的可及性和表達(dá)水平。組蛋白修飾的改變與細(xì)胞分化、發(fā)育和疾病等過(guò)程密切相關(guān)。

熱銷產(chǎn)品

HIST1H3A Recombinant Monoclonal Antibody CSB-RA010418MA1HU

驗(yàn)證數(shù)據(jù)

WB
CSB-RA010418MA1HU WB

Positive WB detected in: MCF7 whole cell lysate,JK whole cell lysate,K562 whole cell lysate,HepG2 whole cell lysate
All lanes: HIST1H3A antibody at 1:1000
Secondary
Goat polyclonal to mouse IgG at 1/50000 dilution
Predicted band size: 16 kDa
Observed band size: 16 kDa

IHC
CSB-RA010418MA1HU IHC

IHC image of CSB-RA010418MA1HU diluted at 1:300 and staining in paraffin-embedded human gastric cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-Mouse IgG labeled by HRP and visualized using 0.05% DAB.

IHC
CSB-RA010418MA1HU IHC

IHC image of CSB-RA010418MA1HU diluted at 1:300 and staining in paraffin-embedded human salivary gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-Mouse IgG labeled by HRP and visualized using 0.05% DAB.

IF
CSB-RA010418MA1HU IF

Immunofluorescence staining of HepG2 cell with CSB-RA010418MA1HU at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Mouse IgG(H+L).

IF
CSB-RA010418MA1HU FC

Immunofluorescence staining of Hela cell with CSB-RA010418MA1HU at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Mouse IgG(H+L).

HIST1H3A Antibodies

HIST1H3A for Homo sapiens (Human)

HIST1H3A Proteins

HIST1H3A Proteins for Homo sapiens (Human)

HIST1H3A Proteins for Mus musculus (Mouse)

HIST1H3A Proteins for Homo sapiens (human)

HIST1H3A ELISA Kit

HIST1H3A ELISA Kit for Homo sapiens (Human)



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