GSTZ1
GSTZ1，全稱為谷胱甘肽S-轉(zhuǎn)移酶ζ1，常用別名包括馬來酰乙酰乙酸異構(gòu)酶。它是人體酪氨酸代謝中的關(guān)鍵參與者，能促進(jìn)代謝過程里某類中間物質(zhì)的轉(zhuǎn)化，讓酪氨酸的分解代謝得以正常完成。一旦GSTZ1功能出現(xiàn)問題，代謝產(chǎn)物會(huì)在體內(nèi)積累，從而引發(fā)遺傳性酪氨酸血癥I型，患者可能出現(xiàn)肝臟受損、腎功能異常等多種癥狀。在臨床治療上，尼替西農(nóng)是常用藥物之一，它通過調(diào)節(jié)代謝通路的上游步驟，減少有毒物質(zhì)的產(chǎn)生，幫助緩解患者癥狀。目前針對(duì)該蛋白缺陷的新療法，比如酶替代治療或基因相關(guān)干預(yù)，仍處于早期研發(fā)階段，未來可能為這類疾病提供更有效的治療方案。
熱銷產(chǎn)品
GSTZ1 Monoclonal Antibody (CSB-MA554791)
驗(yàn)證數(shù)據(jù)
Flow cytometric analysis of GSTZ1 expression in HeLa cells using GSTZ1 antibody. Green, isotype control; red, GSTZ1.
Western blotting analysis using GSTZ1 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with GSTZ1 antibody and HRP-conjugated goat mouse secondary antibody respectively.
GSTZ1 Antibody (CSB-PA009994DSR1HU)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: GSTZ1 antibody at 0.41μg/ml + Mouse liver tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 25, 18, 20 kDa
Observed band size: 25 kDa
Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA009994DSR1HU at dilution of 1:100
GSTZ1 Antibodies
GSTZ1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA009994GA01HU | GSTZ1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA009994DSR1HU | GSTZ1 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA009994DSR2HU | GSTZ1 Antibody | Human | ELISA, IHC |
| CSB-MA554791 | GSTZ1 Monoclonal Antibody | Human | ELISA, WB, FC |
GSTZ1 Proteins
GSTZ1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009994HU CSB-BP009994HU CSB-MP009994HU CSB-EP009994HU-B |
Recombinant Human Maleylacetoacetate isomerase (GSTZ1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP009994HU | Recombinant Human Maleylacetoacetate isomerase (GSTZ1) | E.coli |
