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GRK6

G protein-coupled receptor kinase 6 is a protein in humans that is encoded by GRK6 gene. Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor.

GRK6 Antibodies

GRK6 for Homo sapiens (Human)

GRK6 Proteins

GRK6 Proteins for Rattus norvegicus (Rat)

GRK6 Proteins for Homo sapiens (Human)

GRK6 Proteins for Mus musculus (Mouse)



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