GPSM1
GPSM1，全稱為G蛋白信號調(diào)節(jié)因子1，常用別名包括AGS3。它能與細(xì)胞內(nèi)的G蛋白亞基結(jié)合，協(xié)調(diào)信號傳遞的方向與強(qiáng)度，在細(xì)胞維持結(jié)構(gòu)極性、調(diào)節(jié)移動能力等生理過程中扮演重要角色。GPSM1功能異?？赡荜P(guān)聯(lián)多種疾病：在神經(jīng)系統(tǒng)中，它的表達(dá)變化與精神分裂癥的發(fā)病機(jī)制有關(guān)；在腫瘤領(lǐng)域，肺癌、乳腺癌等癌癥里它的水平異常，可能推動癌細(xì)胞的侵襲和轉(zhuǎn)移。目前針對該蛋白的藥物研發(fā)尚處于早期階段，科研人員正在探索可調(diào)控其活性的小分子化合物，希望未來能為相關(guān)疾病提供新的治療策略。整個過程中，它的作用串聯(lián)起細(xì)胞基礎(chǔ)功能與疾病發(fā)生，是值得深入研究的潛在靶點(diǎn)。
熱銷產(chǎn)品
GPSM1 Antibody (CSB-PA801266LA01HU)
驗(yàn)證數(shù)據(jù)
Immunofluorescence staining of HepG2 cells with CSB-PA801266LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
GPSM1 Antibodies
GPSM1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA009860GA01HU | GPSM1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA008679 | GPSM1 Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-PA801266LA01HU | GPSM1 Antibody | Human | ELISA, IF |
| CSB-PA801266LB01HU | GPSM1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA801266LC01HU | GPSM1 Antibody, FITC conjugated | Human |
GPSM1 Proteins
GPSM1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP801266HU CSB-EP801266HU CSB-BP801266HU CSB-MP801266HU CSB-EP801266HU-B |
Recombinant Human G-protein-signaling modulator 1 (GPSM1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
