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GPR34

GPR34,即G蛋白偶聯(lián)受體34,別名LYPSR1。GPR34基因位于人類X染色體的p11.4區(qū)域。GPR34是一種G蛋白偶聯(lián)受體,具有7個假定的跨膜結(jié)構(gòu)域,通過激活異源三聚體G蛋白將信號傳遞到細(xì)胞內(nèi)部,進(jìn)而激活各種效應(yīng)蛋白,最終導(dǎo)致生理反應(yīng)。GPR34通過與細(xì)胞外的配體結(jié)合,激活細(xì)胞內(nèi)的G蛋白信號通路,進(jìn)而引發(fā)一系列細(xì)胞內(nèi)的反應(yīng),如調(diào)節(jié)細(xì)胞的增殖、分化、遷移等過程。GPR34與多種疾病相關(guān),包括阿爾茨海默病14型、夜盲癥、黏膜相關(guān)淋巴組織淋巴瘤等。

熱銷產(chǎn)品

GPR34 Antibody (CSB-PA891571LA01HU)

驗證數(shù)據(jù)

CSB-PA891571LA01HU

Western Blot
Positive WB detected in: U251 whole cell lysate(30μg), U87 whole cell lysate(30μg), JK whole cell lysate(30μg), Mouse Lung tissue lysate(30μg), Mouse Stomach tissue lysate(30μg)
All lanes: GPR34 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/20000 dilution
Predicted band size: 44 kDa
Observed band size: 44 kDa
Exposure time: 120s

CSB-PA891571LA01HU

IHC image of CSB-PA891571LA01HU diluted at 1:50 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody

CSB-PA891571LA01HU

Immunofluorescence staining of U251 cell with CSB-PA891571LA01HU at 1:30, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

CSB-PA891571LA01HU

Immunofluorescence staining of U251 cell with 5% goat serum, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

CSB-PA891571LA01HU

Immunofluorescence staining of U87 cell with CSB-PA891571LA01HU at 1:30, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

CSB-PA891571LA01HU

Immunofluorescence staining of U87 cell with 5% goat serum, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

GPR34 Antibodies

GPR34 for Homo sapiens (Human)

GPR34 Proteins

GPR34 Proteins for Pan troglodytes (Chimpanzee)

GPR34 Proteins for Pan paniscus (Pygmy chimpanzee) (Bonobo)

GPR34 Proteins for Gorilla gorilla gorilla (Lowland gorilla)

GPR34 Proteins for Mus musculus (Mouse)

GPR34 Proteins for Homo sapiens (Human)



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