GPR3
GPR3，全稱為G蛋白偶聯(lián)受體3，是一種屬于A類孤兒G蛋白偶聯(lián)受體的膜蛋白，在人體內(nèi)廣泛參與多種生理過程。該蛋白具有多種別名，如GPR3受體、G蛋白偶聯(lián)受體3等。GPR3蛋白能夠與多種內(nèi)源性配體結(jié)合，如油酸等，從而激活下游信號通路，參與調(diào)節(jié)情緒、神經(jīng)性疼痛、成癮過程等。研究表明，GPR3蛋白與阿爾茨海默癥、帕金森病等神經(jīng)退行性疾病密切相關(guān)。此外，GPR3蛋白還在脂肪組織產(chǎn)熱和糖酵解調(diào)控中發(fā)揮重要作用，與肥胖癥和糖尿病等代謝性疾病相關(guān)。近年來，研究人員發(fā)現(xiàn)了一種名為AF64394的小分子藥物能夠特異性地抑制GPR3蛋白的活性，為開發(fā)針對神經(jīng)退行性疾病和代謝性疾病的藥物提供了新的思路。
熱銷產(chǎn)品
GPR3 Antibody (CSB-PA009800LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA009800LA01HU at dilution of 1:100
Immunofluorescent analysis of MCF-7 cells using CSB-PA009800LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunofluorescent analysis of A549 cells using CSB-PA009800LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
GPR3 Antibodies
GPR3 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA241224 | GPR3 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA209020 | GPR3 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA009800LA01HU | GPR3 Antibody | Human | ELISA, IHC, IF |
GPR3 Proteins
GPR3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009800HU1 CSB-EP009800HU1 CSB-BP009800HU1 CSB-MP009800HU1 CSB-EP009800HU1-B |
Recombinant Human G-protein coupled receptor 3 (GPR3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009800HU | Recombinant Human G-protein coupled receptor 3 (GPR3) | in vitro E.coli expression system |
GPR3 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009800MO1 CSB-EP009800MO1 CSB-BP009800MO1 CSB-MP009800MO1 CSB-EP009800MO1-B |
Recombinant Mouse G-protein coupled receptor 3 (Gpr3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009800MO | Recombinant Mouse G-protein coupled receptor 3 (Gpr3) | in vitro E.coli expression system |
GPR3 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP811688RA1 CSB-EP811688RA1 CSB-BP811688RA1 CSB-MP811688RA1 CSB-EP811688RA1-B |
Recombinant Rat G-protein coupled receptor 3 (Gpr3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF811688RA | Recombinant Rat G-protein coupled receptor 3 (Gpr3) | in vitro E.coli expression system |
